Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | RIPK1 | Q13546 | 6/20 | 0.49 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.44 |
| ▸ | RORC | P51449 | 2/20 | 0.42 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.41 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.41 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10061592 | 0.88 | RIPK1 (0.61) | RIPK1GPR119RORCABCB1NR1H2 | |
| SCHEMBL15850701 | 0.88 | RIPK1 (0.61) | RIPK1GPR119RORCABCB1NR1H2 | |
| SCHEMBL248353 | 0.88 | RIPK1 (0.61) | RIPK1GPR119RORCABCB1NR1H2 | |
| SCHEMBL27528621 | 0.86 | RORC (0.46) | L3MBTL1RORCNR1H2NR1H3 | |
| SCHEMBL29779454 | 0.86 | RORC (0.46) | L3MBTL1RORCNR1H2NR1H3 | |
| SCHEMBL29779329 | 0.86 | RORC (0.46) | L3MBTL1RORCNR1H2NR1H3 | |
| SCHEMBL22039428 | 0.86 | HTR7 (0.42) | L3MBTL1RORCMEN1KMT2A | |
| SCHEMBL7236411 | 0.86 | HTR7 (0.42) | L3MBTL1RORCMEN1KMT2A | |
| SCHEMBL3738709 | 0.86 | ESR2 (0.40) | L3MBTL1RIPK1GPR119NR1H2NR1H3 | |
| SCHEMBL13701096 | 0.85 | YAP1 (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1198800-C | 2- (2-chlorophenyl) -3, 4-dihydro-2H-pyrrole derivatives | BAYER AG (DE) | 2005-04-27 | — | — | CN | disclosed |
| WO-2002081489-A1 | PALLADIUM-COMPLEXES BASED ON PYRROLINE-METAL COMPLEXES | BAYER CROPSCIENCE AG (DE) | 2002-10-17 | — | — | WO | disclosed |
| CN-1323304-A | 2-hetaryl-3,4-dihydro-2h-pyrrole derivatives | BAYER AG (DE) | 2001-11-21 | — | — | CN | disclosed |
| CN-1309636-A | 2-(2-chlorophenyl)-3,4-dihydro-2H-pyrrol derivs. | BAYER AG (DE) | 2001-08-22 | — | — | CN | disclosed |