Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 3/20 | 0.73 |
| ▸ | CES2 | O00748 | 2/20 | 0.73 |
| ▸ | FNTA | P49354 | 2/20 | 0.59 |
| ▸ | FNTB | P49356 | 2/20 | 0.59 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | PAM | P19021 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL574185 | 0.85 | CES1 (1.00) | CES1CES2FNTAFNTBAKR1B1 | |
| Hydrochloric Acid SCHEMBL3111570 | 0.82 | CES1 (0.94) | CES1CES2FNTAFNTBAKR1B1 | |
| SCHEMBL1493 | 0.80 | CES1 (0.64) | CES1CES2FNTAFNTBAKR1B1 | |
| SCHEMBL27293995 | 0.80 | CES1 (0.64) | CES1CES2FNTAFNTBAKR1B1 | |
| Phenylpyruvate SCHEMBL28203540 | 0.80 | CES1 (0.80) | CES1CES2FNTAFNTBAKR1B1 | |
| SCHEMBL7003190 | 0.80 | CES1 (0.80) | CES1CES2FNTAFNTBAKR1B1 | |
| Phenylpyruvate SCHEMBL43235 | 0.80 | CES1 (0.80) | CES1CES2FNTAFNTBAKR1B1 | |
| SCHEMBL4646048 | 0.79 | CES1 (0.77) | CES1CES2FNTAFNTBAKR1B1 | |
| SCHEMBL10362571 | 0.79 | CES1 (0.61) | CES1CES2FNTAFNTBAKR1B1 | |
| Phenylpyruvate SCHEMBL9217988 | 0.78 | CES1 (0.76) | CES1CES2FNTAFNTBAKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6395894-B2 | BACTERICIDES | MERCK & CO., INC. | 2002-05-28 | — | — | US | claimed |
| US-20010025103-A1 | PROCESS FOR THE SYNTHESIS OF CARBAPENEM INTERMEDIATES, AND COMPOUNDS PRODUCED | MERCK & CO., INC. | 2001-09-27 | — | — | US | claimed |
| EP-1071685-A4 | TITANIUM CATALYZED PREPARATION OF CARBAPENEM INTERMEDIATES | MERCK & CO INC (US) | 2001-07-18 | — | — | EP | claimed |
| EP-1071685-A1 | TITANIUM CATALYZED PREPARATION OF CARBAPENEM INTERMEDIATES | Merck & Co., Inc. (US) | 2001-01-31 | — | — | EP | claimed |
| WO-1999052908-A1 | TITANIUM CATALYZED PREPARATION OF CARBAPENEM INTERMEDIATES | MERCK & CO., INC. (US) | 1999-10-21 | — | — | WO | claimed |
| WO-2011048611-A1 | NOVEL FUSED PYRIDAZINE DERIVATIVES | TORRENT PHARMACEUTICALS LIMITED (IN) | 2011-04-28 | — | — | WO | disclosed |
| CN-100374427-C | Cyclic compound, process for producing the same, and pest control agent | SUMITOMO CHEM TAKEDA AGRO CO (JP) | 2008-03-12 | — | — | CN | disclosed |
| CN-101108830-A | Cyclic compound, process for producing the same, and pest control agent | SUMITOMO CHEM TAKEDA AGRO CO (JP) | 2008-01-23 | — | — | CN | disclosed |
| CN-101003517-A | Cyclic compound, process for producing the same, and pest control agent | SUMITOMO CHEM TAKEDA AGRO CO (JP) | 2007-07-25 | — | — | CN | disclosed |
| US-6972340-B2 | Selective protein tyrosine phosphatatase inhibitors | ABBOTT LABORATORIES (US) | 2005-12-06 | — | — | US | disclosed |
| CN-1649850-A | Cyclic compound, process for producing the same, and pest control agent | SUMITOMO CHEM TAKEDA AGRO CO (JP) | 2005-08-03 | — | — | CN | disclosed |
| US-20050159599-A1 | Cyclic compound, process for producing the same, and pest control agent | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2005-07-21 | — | — | US | disclosed |
| US-4179511-A | Antibacterial 3-(5-tetrazolyl) penam compounds | PFIZER INC. (US) | 1979-12-18 | — | — | US | disclosed |
| US-4143039-A | ANTIBACTERIAL 3-(5-TETRAZOLYL)PENAM COMPOUNDS | PFIZER INC. (US) | 1979-03-06 | — | — | US | disclosed |
| US-4128646-A | ANTIALLERGEN | MITSUBISHI YUKA PHARMACEUTICAL CO., LTD. (JP) | 1978-12-05 | — | — | US | disclosed |
| US-4115385-A | PENICILLINS | PFIZER INC. (US) | 1978-09-19 | — | — | US | disclosed |
| US-3980660-A | ANTIAUERGENS, ANAPHYLACTIC | THE UPJOHN COMPANY (US) | 1976-09-14 | — | — | US | disclosed |
| US-3972911-A | PROPHYLAXIS | THE UPJOHN COMPANY (US) | 1976-08-03 | — | — | US | disclosed |
| US-3941821-A | ANTIINFLAMMATORY, ANALGESICS, ANTIPYRETICS | WILLIAM H. RORER, INC. (US) | 1976-03-02 | — | — | US | disclosed |
| US-3935316-A | Method of use and formulations | THE UPJOHN COMPANY (US) | 1976-01-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010025103-A1 | PROCESS FOR THE SYNTHESIS OF CARBAPENEM INTERMEDIATES, AND COMPOUNDS PRODUCED | HAAO, HACL2, HAO2 | CES1 1543/4885CES2 1741/4885FNTA 2640/4885 |
| US-20050159599-A1 | Cyclic compound, process for producing the same, and pest control agent | CNPY2, CNPY3, HAX1 | CES1 1401/4885CES2 1805/4885FNTA 1161/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.