SCHEMBL729614

SCHEMBL729614

CCCCC(C)[Si](C)(O[Si](C)(C)C)O[Si](C)(C)C

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
DNM1 Q05193 2/20 0.32
OPRM1 P35372 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12261307 0.91 OPRM1 (0.38) DNM1OPRM1
SCHEMBL16576438 0.91 OPRM1 (0.38) DNM1OPRM1
SCHEMBL15199078 0.85 OPRM1 (0.33) DNM1OPRM1
SCHEMBL728957 0.75
SCHEMBL15199076 0.75
SCHEMBL15868427 0.72 DNM1 (0.39) DNM1OPRM1
SCHEMBL27482199 0.71 OPRM1 (0.39) DNM1OPRM1
SCHEMBL16749029 0.70
SCHEMBL10537330 0.70 DNM1 (0.30) DNM1
SCHEMBL690366 0.69 ALDH1A1 (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 77 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-2011527341-A 2011-10-27 JP claimed
US-8017687-B2 Swollen silicone composition and process of producing same MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2011-09-13 US claimed
EP-2296667-A2 SILICONE COMPOSITION Momentive Performance Materials Inc. (US) 2011-03-23 EP claimed
EP-2228053-A1 Swollen silicone composition and process of producing same Momentive Performance Materials Inc. (US) 2010-09-15 EP claimed
JP-2010515566-A 2010-05-13 JP claimed
WO-2010005538-A2 SILICONE COMPOSITION MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2010-01-14 WO claimed
US-20100003201-A1 Silicone composition MOMENTIVE PERFORMANCE MATERIALS, INC. 2010-01-07 US claimed
EP-2108028-A2 METHOD OF APPLYING A COMPOSITION Momentive Performance Materials Inc. (US) 2009-10-14 EP claimed
JP-2009516024-A 2009-04-16 JP claimed
EP-1962791-A1 SWOLLEN SILICONE COMPOSITION, PROCESS OF PRODUCING SAME AND PRODUCTS THEREOF Momentive Performance Materials Inc. (US) 2008-09-03 EP claimed
WO-2008088323-A2 METHOD OF APPLYING A COMPOSITION MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2008-07-24 WO claimed
US-20070160547-A1 Method of applying a composition MOMENTIVE PERFORMANCE MATERIALS INC. 2007-07-12 US claimed
WO-2007061623-A1 SWOLLEN SILICONE COMPOSITION, PROCESS OF PRODUCING SAME AND PRODUCTS THEREOF MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2007-05-31 WO claimed
US-20070112146-A1 Swollen silicone composition, process of producing same and products thereof MOMENTIVE PERFORMANCE MATERIALS INC. 2007-05-17 US claimed
US-20070112112-A1 Swollen silicone composition and process of producing same MOMENTIVE PERFORMANCE MATERIALS INC. 2007-05-17 US claimed
EP-1620068-A1 COSMETIC COMPOSITION COMPRISING A VOLATILE FATTY PHASE L'OREAL (FR) 2006-02-01 EP claimed
WO-2004087077-A1 COSMETIC COMPOSITION COMPRISING A VOLATILE FATTY PHASE L'OREAL (FR) 2004-10-14 WO claimed
US-20040197284-A1 Cosmetic composition comprising a volatile fatty phase L'OREAL S.A. (FR) 2004-10-07 US claimed
EP-3768762-B1 SILICONE POLYMER MOMENTIVE PERFORMANCE MAT INC (US) 2025-02-19 EP disclosed
US-20040197284-A1 Cosmetic composition comprising a volatile fatty phase L'OREAL S.A. (FR) 2004-10-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100003201-A1 Silicone composition CUTA, SMURF1, MMS19 DNM1 3445/4885OPRM1 4733/4885
US-20070112146-A1 Swollen silicone composition, process of producing same and products thereof PIEZO1, SMS, ALG3 DNM1 4596/4885OPRM1 3508/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.