Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17369124 | 0.90 | SMN1; SMN2 (0.57) | SMN1; SMN2ALDH1A1RECQLHPGDKMT2A | |
| SCHEMBL22896894 | 0.87 | LMNA (0.56) | SMN1; SMN2ALDH1A1RECQLHPGDKMT2A | |
| SCHEMBL15869371 | 0.85 | ALDH1A1 (0.60) | ALDH1A1RECQLKMT2AMEN1LMNA | |
| SCHEMBL69400 | 0.81 | SMN1; SMN2 (0.60) | SMN1; SMN2ALDH1A1RECQLHPGDKMT2A | |
| SCHEMBL28825868 | 0.81 | ALDH1A1 (0.62) | SMN1; SMN2ALDH1A1HPGDKMT2AGAA | |
| SCHEMBL4850604 | 0.81 | SMN1; SMN2 (0.60) | SMN1; SMN2ALDH1A1RECQLHPGDKMT2A | |
| SCHEMBL16112407 | 0.79 | SMN1; SMN2 (0.59) | SMN1; SMN2ALDH1A1RECQLHPGDKMT2A | |
| SCHEMBL28923697 | 0.79 | SMN1; SMN2 (0.59) | SMN1; SMN2ALDH1A1RECQLHPGDKMT2A | |
| SCHEMBL16112346 | 0.79 | SMN1; SMN2 (0.62) | SMN1; SMN2ALDH1A1RECQLHPGDKMT2A | |
| SCHEMBL20028706 | 0.79 | SMN1; SMN2 (0.59) | SMN1; SMN2ALDH1A1RECQLHPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8993751-B2 | Process for preparing tetrazole-substituted anthranilic acid diamide derivatives by reacting benzoxazinones with amines | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-03-31 | — | — | US | disclosed |
| US-8916710-B2 | Method for producing tetrazole-substituted anthranilic acid diamide derivatives by reacting pyrazolic acids with anthranilic acid esters | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-12-23 | — | — | US | disclosed |
| US-20140235865-A1 | METHOD FOR PRODUCING TETRAZOLE-SUBSTITUTED ANTHRANILIC ACID DIAMIDE DERIVATIVES BY REACTING PYRAZOLIC ACIDS WITH ANTHRANILIC ACID ESTERS | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-08-21 | — | — | US | disclosed |
| US-20140194623-A1 | PROCESS FOR PREPARING TETRAZOLE-SUBSTITUTED ANTHRANILIC ACID DIAMIDE DERIVATIVES BY REACTING BENZOXAZINONES WITH AMINES | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-07-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140194623-A1 | PROCESS FOR PREPARING TETRAZOLE-SUBSTITUTED ANTHRANILIC ACID DIAMIDE DERIVATIVES BY REACTING BENZOXAZINONES WITH AMINES | DAO, QDPR, DHX15 | SMN1; SMN2 4585/4885ALDH1A1 1030/4885RECQL 164/4885 |
| US-20140235865-A1 | METHOD FOR PRODUCING TETRAZOLE-SUBSTITUTED ANTHRANILIC ACID DIAMIDE DERIVATIVES BY REACTING PYRAZOLIC ACIDS WITH ANTHRANILIC ACID ESTERS | DAO, QPCT, AADAT | SMN1; SMN2 4850/4885ALDH1A1 969/4885RECQL 906/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.