SCHEMBL15876277

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL17486450	0.94	POLB (0.41)	MTNR1AMTNR1BS1PR1ATMRIPK1
	SCHEMBL13662612	0.87	ATM (0.44)	S1PR1ATMMAPTTDP1LMNA
	SCHEMBL14205020	0.87	KMT2A (0.46)	S1PR1ATMMAPTTDP1LMNA
	SCHEMBL8421187	0.87	VSIR (0.44)	S1PR1ATMMAPTTDP1LMNA
	SCHEMBL6140645	0.86	S1PR1 (0.40)	MTNR1AMTNR1BS1PR1ATMMAPT
	SCHEMBL8139519	0.86	TPSAB1 (0.45)	S1PR1ATMMAPTTDP1LMNA
	SCHEMBL1227911	0.86	GAA (0.53)	S1PR1MAPTLMNAGAASMN1; SMN2
	SCHEMBL1109881	0.86	S1PR1 (0.42)	S1PR1ATMMAPTTDP1LMNA
	SCHEMBL13605089	0.86	ANPEP (0.50)	GAACA1
	SCHEMBL14238298	0.86	PYCR1 (0.44)	S1PR1ATMMAPTLMNAHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.