Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.76 |
| ▸ | RAB9A | P51151 | 4/20 | 0.76 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.76 |
| ▸ | CA12 | O43570 | 2/20 | 0.68 |
| ▸ | CA2 | P00918 | 2/20 | 0.68 |
| ▸ | CA9 | Q16790 | 2/20 | 0.68 |
| ▸ | CA1 | P00915 | 1/20 | 0.68 |
| ▸ | LMNA | P02545 | 3/20 | 0.66 |
| ▸ | GAA | P10253 | 2/20 | 0.66 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.66 |
| ▸ | IDO1 | P14902 | 1/20 | 0.63 |
| ▸ | MAOA | P21397 | 1/20 | 0.63 |
| ▸ | MAOB | P27338 | 1/20 | 0.63 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.58 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.58 |
| ▸ | MAPT | P10636 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4020005 | 0.94 | NPC1 (0.68) | NPC1RAB9ASMN1; SMN2CA12CA2 | |
| Methane SCHEMBL8530831 | 0.92 | NPC1 (0.66) | NPC1RAB9ASMN1; SMN2CA12CA2 | |
| Methane SCHEMBL2796518 | 0.92 | NPC1 (0.66) | NPC1RAB9ASMN1; SMN2CA12CA2 | |
| SCHEMBL11746910 | 0.92 | NPC1 (0.66) | NPC1RAB9ASMN1; SMN2CA12CA2 | |
| SCHEMBL28883056 | 0.90 | NPC1 (0.63) | NPC1RAB9ASMN1; SMN2CA12CA2 | |
| SCHEMBL156779 | 0.87 | KMT2A (0.66) | NPC1RAB9ASMN1; SMN2LMNAGAA | |
| SCHEMBL6524477 | 0.86 | RAB9A (1.00) | NPC1RAB9ASMN1; SMN2CA12CA2 | |
| SCHEMBL15550723 | 0.83 | HDAC3 (0.68) | CA12CA2CA9CA1LMNA | |
| SCHEMBL4019998 | 0.83 | NPC1 (0.70) | NPC1RAB9ASMN1; SMN2CA12CA2 | |
| SCHEMBL1860288 | 0.83 | NPC1 (0.70) | NPC1RAB9ASMN1; SMN2CA12CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1771162-B1 | CAPSAICIN INHIBITORS FOR THE TREATMENT OF OBESITY-RELATED DISORDERS | XENIA PHARMA (DK) | 2013-06-05 | — | — | EP | claimed |
| US-8455504-B2 | Inhibition of the activity of the capsaicin receptor in the treatment of type 1 diabetes, type 2 diabetes, impaired glucose tolerance or insulin resistance | XENIA PHARMA (DK) | 2013-06-04 | — | — | US | claimed |
| EP-4653434-A1 | CRYSTALLINE SALT OF MACROPA-(OCH2CH2)-PH-NCS | Bayer Aktiengesellschaft (DE) | 2025-11-26 | — | — | EP | disclosed |
| US-9918473-B2 | Use of aryl carbamates in agriculture and other plant-related areas | North Carolian State University (US) | 2018-03-20 | — | — | US | disclosed |
| US-20160353739-A1 | USE OF ARYL CARBAMATES IN AGRICULTURE AND OTHER PLANT-RELATED AREAS | UNIV NORTH CAROLINA STATE (US) | 2016-12-08 | — | — | US | disclosed |
| US-9439436-B2 | Use of aryl carbamates in agriculture and other plant-related areas | NORTH CAROLINA STATE UNIVERSITY (US) | 2016-09-13 | — | — | US | disclosed |
| US-20150327552-A1 | USE OF ARYL CARBAMATES IN AGRICULTURE AND OTHER PLANT-RELATED AREAS | UNIV NORTH CAROLINA STATE (US) | 2015-11-19 | — | — | US | disclosed |
| US-9125408-B2 | Use of aryl carbamates in agriculture and other plant-related areas | NORTH CAROLINA STATE UNIVERSITY (US) | 2015-09-08 | — | — | US | disclosed |
| US-8884022-B2 | Inhibition of bacterial biofilms with aryl carbamates | NORTH CAROLINA STATE UNIVERSITY (US) | 2014-11-11 | — | — | US | disclosed |
| US-20130172187-A1 | USE OF ARYL CARBAMATES IN AGRICULTURE AND OTHER PLANT-RELATED AREAS | NORTH CAROLINA STATE UNIVERSITY | 2013-07-04 | — | — | US | disclosed |
| EP-1771162-B1 | CAPSAICIN INHIBITORS FOR THE TREATMENT OF OBESITY-RELATED DISORDERS | XENIA PHARMA (DK) | 2013-06-05 | — | — | EP | disclosed |
| EP-1771162-A2 | CAPSAICIN INHIBITORS FOR TREATING OBESITY AND RELATED DISORDERS | NOVO NORDISK A/S (DK) | 2007-04-11 | — | — | EP | disclosed |
| US-20060264480-A1 | Novel thiocarbamic acid derivatives and the pharmaceutical compositions containing the same | SUH YOUNG G | 2006-11-23 | — | — | US | disclosed |
| WO-2006007851-A2 | CAPSAICIN INHIBITORS FOR TREATING OBESITY AND-RELATED DISORDERS | NOVO NORDISK A/S (DK) | 2006-01-26 | — | — | WO | disclosed |
| EP-1311477-A4 | NOVEL THIOCARBAMIC ACID DERIVATIVES AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | PACIFIC CORP (KR) | 2005-01-12 | — | — | EP | disclosed |
| US-20030203944-A1 | Novel thiocarbamic acid derivatives and the pharmaceutical compositions containing the same | PACIFIC CORPORATION (KR) | 2003-10-30 | — | — | US | disclosed |
| EP-1311477-A1 | NOVEL THIOCARBAMIC ACID DERIVATIVES AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | PACIFIC CORPORATION (KR) | 2003-05-21 | — | — | EP | disclosed |
| WO-2002016317-A1 | NOVEL THIOCARBAMIC ACID DERIVATIVES AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | PACIFIC CORPORATION (KR) | 2002-02-28 | — | — | WO | disclosed |
| US-5637731-A | CHOLINERGIC AGENTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1997-06-10 | — | — | US | disclosed |
| US-5550257-A | TREATING CENTRAL CHOLINERGIC DYSFUNCTION | AMERICAN CYANAMID COMPANY (US) | 1996-08-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130172187-A1 | USE OF ARYL CARBAMATES IN AGRICULTURE AND OTHER PLANT-RELATED AREAS | CTRC, ACE, DDT | NPC1 2027/4885RAB9A 1963/4885SMN1; SMN2 4442/4885 |
| US-20160353739-A1 | USE OF ARYL CARBAMATES IN AGRICULTURE AND OTHER PLANT-RELATED AREAS | CTRC, ACE, DDT | NPC1 2027/4885RAB9A 1963/4885SMN1; SMN2 4442/4885 |
| US-20060264480-A1 | Novel thiocarbamic acid derivatives and the pharmaceutical compositions containing the same | TRPV1, TRPA1, TRPV5 | NPC1 2332/4885RAB9A 1122/4885SMN1; SMN2 1555/4885 |
| US-20150327552-A1 | USE OF ARYL CARBAMATES IN AGRICULTURE AND OTHER PLANT-RELATED AREAS | CTRC, ACE, DDT | NPC1 2027/4885RAB9A 1963/4885SMN1; SMN2 4442/4885 |
| US-20030203944-A1 | Novel thiocarbamic acid derivatives and the pharmaceutical compositions containing the same | TRPV1, TRPA1, TRPV5 | NPC1 2332/4885RAB9A 1122/4885SMN1; SMN2 1555/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.