Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.70 |
| ▸ | RAB9A | P51151 | 4/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.70 |
| ▸ | CA12 | O43570 | 2/20 | 0.63 |
| ▸ | CA2 | P00918 | 2/20 | 0.63 |
| ▸ | CA9 | Q16790 | 2/20 | 0.63 |
| ▸ | CA1 | P00915 | 1/20 | 0.63 |
| ▸ | LMNA | P02545 | 3/20 | 0.61 |
| ▸ | GAA | P10253 | 2/20 | 0.61 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.61 |
| ▸ | IDO1 | P14902 | 1/20 | 0.59 |
| ▸ | MAOA | P21397 | 1/20 | 0.59 |
| ▸ | MAOB | P27338 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.54 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28883052 | 0.98 | NPC1 (0.68) | NPC1RAB9ASMN1; SMN2CA12CA2 | |
| SCHEMBL159163 | 0.83 | NPC1 (0.76) | NPC1RAB9ASMN1; SMN2CA12CA2 | |
| SCHEMBL6524477 | 0.83 | RAB9A (1.00) | NPC1RAB9ASMN1; SMN2CA12CA2 | |
| SCHEMBL28581076 | 0.80 | NPC1 (0.55) | NPC1RAB9ASMN1; SMN2CA12CA2 | |
| SCHEMBL5889607 | 0.79 | NPC1 (0.70) | NPC1RAB9ASMN1; SMN2CA12CA2 | |
| SCHEMBL525787 | 0.79 | NPC1 (0.70) | NPC1RAB9ASMN1; SMN2CA12CA2 | |
| SCHEMBL1860288 | 0.79 | NPC1 (0.70) | NPC1RAB9ASMN1; SMN2CA12CA2 | |
| SCHEMBL159162 | 0.79 | CA12 (0.63) | NPC1RAB9ASMN1; SMN2CA12CA2 | |
| SCHEMBL1056090 | 0.78 | ALOX12 (0.68) | SMN1; SMN2CA12CA2CA9CA1 | |
| SCHEMBL9176170 | 0.78 | NPC1 (0.68) | NPC1RAB9ASMN1; SMN2CA12CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110683975-B | Synthesis method of dialkyl amino alkyl dithioformate | 成都理工大学 | 2021-04-09 | — | — | CN | claimed |
| EP-1940787-A4 | NOVEL IDO INHIBITORS AND METHODS OF USE THEREOF | LANKENAU INST MEDICAL RES (US) | 2009-07-01 | — | — | EP | claimed |
| EP-1940787-A1 | NOVEL IDO INHIBITORS AND METHODS OF USE THEREOF | Lankenau Institute for Medical Research (US) | 2008-07-09 | — | — | EP | claimed |
| WO-2007050963-A1 | NOVEL IDO INHIBITORS AND METHODS OF USE THEREOF | LANKENAU INSTITUTE FOR MEDICAL RESEARCH (US) | 2007-05-03 | — | — | WO | claimed |
| US-20200087648-A1 | PARKIN LIGASE ACTIVATION METHODS AND COMPOSITIONS | NYSNOBIO IRELAND DAC (IE) | 2020-03-19 | — | — | US | disclosed |
| US-10155936-B2 | Parkin ligase activation methods and compositions | An2H Discovery Limited (IE) | 2018-12-18 | — | — | US | disclosed |
| US-20160160205-A1 | PARKIN LIGASE ACTIVATION METHODS AND COMPOSITIONS | An2H Discovery Limited (IE) | 2016-06-09 | — | — | US | disclosed |
| CN-1211210-A | Process for producing dip-coated articles | BASF AG (DE) | 1999-03-17 | — | — | CN | disclosed |
| EP-0427624-B1 | Thermoplastic elastomer based on polynorbornene and polyvinyl chloride | ATOCHEM ELF SA (FR) | 1996-01-17 | — | — | EP | disclosed |
| EP-0431996-B1 | Elastic memory thermoplastic compositions and process for their preparation | ATOCHEM ELF SA (FR) | 1995-07-05 | — | — | EP | disclosed |
| EP-0394113-B1 | Thermoplastic elastomer based on an ethylene/acrylate copolymer and on polynorbornene | ATOCHEM ELF SA (FR) | 1994-06-29 | — | — | EP | disclosed |
| EP-0384822-B1 | THERMOPLASTIC ELASTOMER MADE OF ETHYLENE/ALPHA-OLEFIN COPOLYMER AND POLYNORBORNENE | ELF ATOCHEM S.A. (FR) | 1993-09-29 | — | — | EP | disclosed |
| EP-0431996-A1 | Elastic memory thermoplastic compositions and process for their preparation | ELF ATOCHEM S.A. (FR) | 1991-06-12 | — | — | EP | disclosed |
| WO-1991007464-A1 | THERMOPLASTIC ELASTOMER BASED ON POLYNORBORNENE AND VINYL POLYCHLORIDE | ATOCHEM (FR) | 1991-05-30 | — | — | WO | disclosed |
| WO-1991007460-A1 | FILM MEMORY THERMOPLASTIC COMPOSITIONS AND METHOD FOR PREPARING SAME | ATOCHEM (FR) | 1991-05-30 | — | — | WO | disclosed |
| WO-1990010033-A1 | THERMOPLASTIC ELASTOMER BASED ON ETHYLENE/α-OLEFIN COPOLYMER AND POLYNORBORNENE | NORSOLOR (FR) | 1990-09-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10155936-B2 | Parkin ligase activation methods and compositions | PINK1, XIAP, STUB1 | NPC1 1493/4885RAB9A 1746/4885SMN1; SMN2 404/4885 |
| US-20200087648-A1 | PARKIN LIGASE ACTIVATION METHODS AND COMPOSITIONS | PINK1, XIAP, STUB1 | NPC1 1493/4885RAB9A 1746/4885SMN1; SMN2 404/4885 |
| US-20160160205-A1 | PARKIN LIGASE ACTIVATION METHODS AND COMPOSITIONS | PINK1, XIAP, STUB1 | NPC1 1493/4885RAB9A 1746/4885SMN1; SMN2 404/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.