Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLO1 | Q04760 | 5/20 | 0.45 |
| ▸ | GRIN2B | Q13224 | 14/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17362187 | 0.82 | APP (0.47) | GLO1GRIN2BGRIN1 | |
| SCHEMBL17362391 | 0.77 | GRIN2B (0.35) | GLO1GRIN2BGRIN1 | |
| SCHEMBL31126987 | 0.70 | ADORA2A (0.36) | GLO1HDAC3HDAC1HDAC2 | |
| SCHEMBL15339570 | 0.70 | CCR1 (0.39) | GLO1 | |
| SCHEMBL31126947 | 0.70 | FGFR1 (0.44) | GLO1 | |
| SCHEMBL4292040 | 0.67 | GLO1 (0.40) | GLO1 | |
| SCHEMBL13195335 | 0.67 | MKNK2 (0.40) | — | |
| SCHEMBL17362285 | 0.65 | ALOX5AP (0.41) | — | |
| SCHEMBL5779450 | 0.65 | MTNR1A (0.60) | — | |
| SCHEMBL2135621 | 0.64 | ALDH1A1 (0.48) | HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9884878-B2 | FLAP modulators | JANSSEN PHARMACEUTICA NV (BE) | 2018-02-06 | — | — | US | disclosed |
| US-20150259357-A1 | FLAP MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2015-09-17 | — | — | US | disclosed |
| US-9079866-B2 | Flap modulators | JANSSEN PHARMACEUTICA NV (BE) | 2015-07-14 | — | — | US | disclosed |
| US-20140221311-A1 | FLAP MODULATORS | JANSSEN PHARMACEUTICA NV (US) | 2014-08-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150259357-A1 | FLAP MODULATORS | PGF, FEN1, TBXA2R | GLO1 722/4885GRIN2B 3206/4885GRIN1 2844/4885 |
| US-20140221311-A1 | FLAP MODULATORS | PGF, FEN1, TBXA2R | GLO1 722/4885GRIN2B 3206/4885GRIN1 2844/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.