Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCF1 | P14598 | 3/20 | 0.52 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.39 |
| ▸ | NOS2 | P35228 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20789917 | 0.76 | BACE1 (0.46) | BACE1 | |
| SCHEMBL4268344 | 0.76 | NCF1 (0.62) | NCF1PTK2LMNACYP1A2HIF1A | |
| SCHEMBL169490 | 0.75 | ALDH1A1 (0.47) | KDM4ELMNAHIF1AMAPTSMN1; SMN2 | |
| SCHEMBL13701721 | 0.74 | NCF1 (0.60) | NCF1PTK2LMNARAB9ANPC1 | |
| SCHEMBL10706825 | 0.73 | MAPT (0.50) | KDM4ELMNAHIF1AMAPTSMN1; SMN2 | |
| SCHEMBL27944767 | 0.73 | PTK2 (0.60) | NCF1PTK2KDM4ELMNARAB9A | |
| SCHEMBL28565830 | 0.72 | TLR8 (0.37) | KDM4ERAB9ANPC1PKMCYP1A2 | |
| SCHEMBL8520461 | 0.72 | RAB9A (0.55) | KDM4ELMNARAB9ANPC1PKM | |
| SCHEMBL12014904 | 0.72 | NCF1 (0.68) | NCF1PTK2KDM4ELMNARAB9A | |
| SCHEMBL25488411 | 0.71 | NCF1 (0.56) | NCF1PTK2KDM4ELMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4420308-A | Process for the production of reserve effects on polyester textiles and polyester/cellulose mixed fibre textiles: discharge printing with disperse azo dye with alkyl or alkoxy carbonyl, cyand and hydroxy phenyl group | CASSELLA AKTIENGESELLSCHAFT (DE) | 1983-12-13 | — | — | US | claimed |
| US-20160093413-A1 | ELECTROCONDUCTIVE COMPOSITION, ELECTRICAL CONDUCTOR, LAMINATE AND METHOD FOR PRODUCING SAME, ELECTROCONDUCTIVE FILM, AND SOLID ELECTROLYTE CONDENSER | MITSUBISHI RAYON CO., LTD. (JP) | 2016-03-31 | — | — | US | disclosed |
| US-20110092488-A1 | Quninoline Methanol Compounds for the Treatment and Prevention of Parasitic Infections | DOW GEOFFREY | 2011-04-21 | — | — | US | disclosed |
| US-4420308-A | Process for the production of reserve effects on polyester textiles and polyester/cellulose mixed fibre textiles: discharge printing with disperse azo dye with alkyl or alkoxy carbonyl, cyand and hydroxy phenyl group | CASSELLA AKTIENGESELLSCHAFT (DE) | 1983-12-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110092488-A1 | Quninoline Methanol Compounds for the Treatment and Prevention of Parasitic Infections | MTX1, MTX2, NQO2 | NCF1 2699/4885PTK2 1387/4885KDM4E 1259/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.