Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.46 |
| ▸ | CHUK | O15111 | 1/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.43 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.43 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.43 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.43 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.43 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 6/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.42 |
| ▸ | RELA | Q04206 | 3/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 5/20 | 0.41 |
| ▸ | HPGD | P15428 | 4/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15850837 | 0.92 | NPC1 (0.45) | NR1H4CHUKCASP3TXNRD1SENP8 | |
| SCHEMBL13379319 | 0.92 | NPC1 (0.43) | NR1H4CHUKCASP3TXNRD1SENP8 | |
| SCHEMBL13379321 | 0.91 | NPC1 (0.54) | NR1H4CHUKCASP3TXNRD1SENP8 | |
| SCHEMBL13379323 | 0.89 | GPR55 (0.55) | NR1H4CHUKCASP3TXNRD1SENP8 | |
| SCHEMBL13606306 | 0.88 | NPC1 (0.51) | NR1H4CHUKCASP3TXNRD1SENP8 | |
| SCHEMBL13379308 | 0.87 | NPC1 (0.48) | CHUKCASP3TXNRD1SENP8SENP7 | |
| SCHEMBL13376120 | 0.87 | TSHR (0.45) | CHUKCASP3TXNRD1SENP8SENP7 | |
| SCHEMBL20391191 | 0.87 | NR1H4 (0.43) | NR1H4CHUKCASP3TXNRD1SENP8 | |
| SCHEMBL13379333 | 0.85 | KDM4E (0.44) | CHUKCASP3TXNRD1SENP8SENP7 | |
| SCHEMBL13379331 | 0.84 | ALDH1A1 (0.55) | NR1H4CHUKCASP3TXNRD1SENP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140249311-A1 | Iron Containing Hydrosilylation Catalysts and Compositions Containing the Catalysts | DOW CORNING CORPORATION | 2014-09-04 | — | — | US | disclosed |
| US-20140213690-A1 | Titanium Containing Complex and Condensation Reaction Catalysts, Methods for Preparing the Catalysts, and Compositions Containing the Catalysts | DOW CORNING CORPORATION (US) | 2014-07-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140249311-A1 | Iron Containing Hydrosilylation Catalysts and Compositions Containing the Catalysts | TFRC, FTH1, HAMP | NR1H4 3448/4885CHUK 3576/4885CASP3 4485/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.