Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.45 |
| ▸ | RAB9A | P51151 | 6/20 | 0.45 |
| ▸ | TSHR | P16473 | 4/20 | 0.45 |
| ▸ | TP53 | P04637 | 3/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | CHUK | O15111 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.39 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.39 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13376120 | 0.93 | TSHR (0.45) | NPC1RAB9ATSHRTP53NPSR1 | |
| SCHEMBL20391191 | 0.93 | NR1H4 (0.43) | NPC1RAB9ATSHRTP53NPSR1 | |
| SCHEMBL15919102 | 0.92 | NR1H4 (0.46) | NPC1RAB9ATSHRTP53NPSR1 | |
| SCHEMBL13379312 | 0.88 | GPR55 (0.45) | NPC1RAB9ATSHRTP53NPSR1 | |
| SCHEMBL13379325 | 0.88 | MAPT (0.44) | NPC1RAB9ATSHRTP53NPSR1 | |
| SCHEMBL13379310 | 0.87 | TSHR (0.43) | NPC1RAB9ATSHRTP53NPSR1 | |
| SCHEMBL13379332 | 0.87 | TSHR (0.53) | NPC1RAB9ATSHRTP53NPSR1 | |
| SCHEMBL13379321 | 0.85 | NPC1 (0.54) | NPC1RAB9ATSHRTP53NPSR1 | |
| SCHEMBL13379319 | 0.84 | NPC1 (0.43) | NPC1RAB9ATSHRTP53NPSR1 | |
| SCHEMBL13606297 | 0.84 | TSHR (0.50) | NPC1RAB9ATSHRTP53NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140275329-A1 | Ruthenium Containing Hydrosilylation Catalysts And Compositions Containing The Catalysts | DOW SILICONES CORPORATION | 2014-09-18 | — | — | US | disclosed |
| US-20140249311-A1 | Iron Containing Hydrosilylation Catalysts and Compositions Containing the Catalysts | DOW CORNING CORPORATION | 2014-09-04 | — | — | US | disclosed |
| US-20140231702-A1 | Cobalt Containing Hydrosilylation Catalysts and Compositions Containing the Catalysts | DOW CORNING CORPORATION | 2014-08-21 | — | — | US | disclosed |
| US-20140213690-A1 | Titanium Containing Complex and Condensation Reaction Catalysts, Methods for Preparing the Catalysts, and Compositions Containing the Catalysts | DOW CORNING CORPORATION (US) | 2014-07-31 | — | — | US | disclosed |
| US-20140200349-A1 | Manganese Containing Hydrosilylation Catalysts and Compositions Containing the Catalysts | DOW CORNING CORPORATION (US) | 2014-07-17 | — | — | US | disclosed |
| US-20140182483-A1 | Titanium Containing Hydrosilylation Catalysts And Compositions Containing The Catalysts | DOW CORNING CORPORATION | 2014-07-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140200349-A1 | Manganese Containing Hydrosilylation Catalysts and Compositions Containing the Catalysts | HIRA, MMS19, ALG8 | NPC1 2324/4885RAB9A 1585/4885TSHR 4238/4885 |
| US-20140231702-A1 | Cobalt Containing Hydrosilylation Catalysts and Compositions Containing the Catalysts | HIRA, CROCC, GYPA | NPC1 2202/4885RAB9A 1939/4885TSHR 4151/4885 |
| US-20140249311-A1 | Iron Containing Hydrosilylation Catalysts and Compositions Containing the Catalysts | TFRC, FTH1, HAMP | NPC1 2860/4885RAB9A 1335/4885TSHR 3187/4885 |
| US-20140182483-A1 | Titanium Containing Hydrosilylation Catalysts And Compositions Containing The Catalysts | ITGA1, TMT1A, ITGA2 | NPC1 3589/4885RAB9A 825/4885TSHR 2404/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.