Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 10/20 | 0.52 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.37 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | GBA1 | P04062 | 1/20 | 0.36 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.36 |
| ▸ | CETP | P11597 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15933535 | 0.87 | GPR119 (0.49) | GPR119EGLN2ESR2PGGT1BCETP | |
| SCHEMBL15933678 | 0.86 | CSNK1D (0.43) | GPR119ESR2GBA1 | |
| SCHEMBL15933643 | 0.84 | GPR119 (0.45) | GPR119ESR2GBA1 | |
| SCHEMBL15933677 | 0.81 | GPR119 (0.53) | GPR119EGLN2BRD4CREBBP | |
| SCHEMBL15933697 | 0.80 | GPR119 (0.47) | GPR119ESR2GBA1 | |
| SCHEMBL17984905 | 0.79 | ESR2 (0.40) | ESR2 | |
| SCHEMBL20140942 | 0.79 | CKS1B (0.49) | GPR119ESR2GBA1 | |
| SCHEMBL25431827 | 0.77 | GPR119 (0.43) | GPR119ESR2 | |
| SCHEMBL24689592 | 0.76 | PDE10A (0.42) | GPR119GBA1 | |
| SCHEMBL15933477 | 0.76 | HDAC4 (0.40) | GPR119ESR2GBA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014117318-A1 | NOVEL TRIAZOLE ANTIFUNGAL COMPOUNDS, AND PHARMACEUTICAL COMPOSITION, PREPARATION METHOD, AND APPLICATION THEREOF | 中国科学院上海药物研究所 (CN) | 2014-08-07 | — | — | WO | disclosed |