SCHEMBL15935629

SCHEMBL15935629

CCc1cc(Oc2ncc(Cl)cc2F)ccc1-c1c(O)c(C)nn(C)c1=O

nearest known ligand 0.41

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 9/20 0.41
KCNH2 Q12809 5/20 0.41
DRD1 P21728 8/20 0.39
PPARG P37231 1/20 0.39
FPR2 P25090 1/20 0.36
PROKR1 Q8TCW9 1/20 0.36
ALDH1A1 P00352 1/20 0.34
LMNA P02545 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
GPR55 Q9Y2T6 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15935598 0.83 RAB9A (0.46) PPARGALDH1A1LMNASMN1; SMN2
SCHEMBL15935633 0.78 POLB (0.46) SMN1; SMN2
SCHEMBL15935636 0.78 ALDH1A1 (0.39) PPARGALDH1A1LMNASMN1; SMN2GPR55
SCHEMBL15935705 0.77 POLB (0.34) FPR2PROKR1
SCHEMBL15935710 0.76 MAPK1 (0.44) KCNH2LMNA
SCHEMBL15935597 0.76 GRM2 (0.37) KCNH2
SCHEMBL18131570 0.75 MAPT (0.41) LMNA
SCHEMBL15935609 0.74 LMNA (0.48) PPARGALDH1A1LMNASMN1; SMN2
SCHEMBL15935617 0.74 CTSD (0.37) ALDH1A1LMNASMN1; SMN2GPR55
SCHEMBL15935606 0.74 CTSD (0.37) PPARGALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2014119770-A1 PYRIDAZINONE COMPOUND AND HERBICIDE COMPRISING SAME 住友化学株式会社 (JP) 2014-08-07 WO disclosed