Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CRHR1 | P34998 | 10/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | SPR | P35270 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | KAT2B | Q92831 | 2/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18131570 | 0.85 | MAPT (0.41) | POLBCRHR1MAPTSPR | |
| SCHEMBL15935619 | 0.85 | ANPEP (0.38) | ADORA2AADORA2B | |
| SCHEMBL15935705 | 0.82 | POLB (0.34) | POLBCRHR1KDM4EBRD4 | |
| SCHEMBL15935598 | 0.78 | RAB9A (0.46) | POLBMAPTKDM4ESMN1; SMN2 | |
| SCHEMBL15935710 | 0.78 | MAPK1 (0.44) | MAPT | |
| SCHEMBL15935629 | 0.78 | LTA4H (0.41) | SMN1; SMN2 | |
| SCHEMBL15935707 | 0.78 | CTSD (0.42) | SMN1; SMN2 | |
| SCHEMBL15935597 | 0.77 | GRM2 (0.37) | BRD4 | |
| SCHEMBL17224797 | 0.77 | ALDH1A1 (0.43) | POLBMAPTKDM4ESMN1; SMN2 | |
| SCHEMBL17224801 | 0.77 | XDH (0.49) | POLBMAPTKDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014119770-A1 | PYRIDAZINONE COMPOUND AND HERBICIDE COMPRISING SAME | 住友化学株式会社 (JP) | 2014-08-07 | — | — | WO | disclosed |