SCHEMBL15935705

SCHEMBL15935705

CCc1cc(Oc2ccc(C(F)(F)F)cc2)ccc1-c1c(O)c(C)nn(C)c1=O

nearest known ligand 0.36

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.34
NR1D1 P20393 2/20 0.34
NPBWR1 P48145 2/20 0.33
CRHR1 P34998 2/20 0.33
MCHR1 Q99705 1/20 0.33
FPR2 P25090 1/20 0.33
PROKR1 Q8TCW9 1/20 0.33
BRD4 O60885 1/20 0.33
KDM4E B2RXH2 1/20 0.33
SCN9A Q15858 1/20 0.33
PDE2A O00408 1/20 0.33
EGLN1 Q9GZT9 1/20 0.33
AGER Q15109 1/20 0.33
FFAR1 O14842 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15935710 0.89 MAPK1 (0.44) SCN9AFFAR1
SCHEMBL15935632 0.86 PDE2A (0.38) POLBPDE2A
SCHEMBL15935598 0.84 RAB9A (0.46) POLBKDM4EFFAR1
SCHEMBL15935633 0.82 POLB (0.46) POLBCRHR1BRD4KDM4E
SCHEMBL18131570 0.80 MAPT (0.41) POLBCRHR1
SCHEMBL15935619 0.78 ANPEP (0.38)
SCHEMBL15935629 0.77 LTA4H (0.41) FPR2PROKR1
SCHEMBL15935597 0.76 GRM2 (0.37) BRD4SCN9A
SCHEMBL15935707 0.75 CTSD (0.42)
SCHEMBL15935609 0.75 LMNA (0.48) POLBFFAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2014119770-A1 PYRIDAZINONE COMPOUND AND HERBICIDE COMPRISING SAME 住友化学株式会社 (JP) 2014-08-07 WO disclosed