SCHEMBL15935707

SCHEMBL15935707

CCc1cc(Oc2nc3ccccc3s2)ccc1-c1c(O)c(C)nn(C)c1=O

nearest known ligand 0.42

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
CTSD P07339 1/20 0.42
CYP1A2 P05177 1/20 0.41
CYP3A4 P08684 1/20 0.41
CYP2D6 P10635 1/20 0.41
CYP2C19 P33261 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
LTA4H P09960 16/20 0.39
EPHX2 P34913 3/20 0.39
KCNH2 Q12809 3/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15935606 0.89 CTSD (0.37) CTSDSMN1; SMN2EPHX2
SCHEMBL15935633 0.78 POLB (0.46) SMN1; SMN2
SCHEMBL18131570 0.75 MAPT (0.41)
SCHEMBL15935705 0.75 POLB (0.34)
SCHEMBL15935619 0.73 ANPEP (0.38)
SCHEMBL15935629 0.73 LTA4H (0.41) SMN1; SMN2LTA4HKCNH2
SCHEMBL15935617 0.73 CTSD (0.37) CTSDSMN1; SMN2
SCHEMBL15935636 0.73 ALDH1A1 (0.39) CYP1A2CYP3A4CYP2C19SMN1; SMN2
SCHEMBL10192940 0.72 CYP1A2 (0.43) CTSDCYP1A2CYP3A4CYP2D6CYP2C19
SCHEMBL15935710 0.71 MAPK1 (0.44) KCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2014119770-A1 PYRIDAZINONE COMPOUND AND HERBICIDE COMPRISING SAME 住友化学株式会社 (JP) 2014-08-07 WO disclosed