SCHEMBL15944285

SCHEMBL15944285

Cc1ccc(SCC(C)(C)C2CC(=O)C(c3c(C)cc(C)cc3C)=C(O)C2)cc1

nearest known ligand 0.34

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.34
KMT2A Q03164 2/20 0.34
HPGD P15428 1/20 0.31
CRBN Q96SW2 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14235156 0.91 PPARD (0.33)
SCHEMBL15944261 0.90 MEN1 (0.34) MEN1KMT2AHPGD
SCHEMBL15944283 0.85 DAO (0.31)
SCHEMBL14234565 0.81 ALOX5 (0.31)
SCHEMBL17193334 0.81 MAOA (0.32) MEN1KMT2AHPGD
SCHEMBL15945499 0.79 ALDH1A1 (0.38) CRBN
SCHEMBL15944271 0.79 DAO (0.30)
SCHEMBL15944252 0.77 MEN1 (0.34) MEN1KMT2AHPGD
SCHEMBL10079487 0.76
SCHEMBL15944254 0.76 KMT2A (0.36) MEN1KMT2AHPGDCRBN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9414588-B2 Herbicide composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2016-08-16 US disclosed
US-20150289505-A1 HERBICIDE COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-10-15 US disclosed
US-9101140-B2 Cyclohexanone compounds and herbicides comprising the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-08-11 US disclosed
US-20140228219-A1 CYCLOHEXANONE COMPOUNDS AND HERBICIDES COMPRISING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2014-08-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140228219-A1 CYCLOHEXANONE COMPOUNDS AND HERBICIDES COMPRISING THE SAME CBR3, CBR1, CYP2S1 MEN1 4391/4885KMT2A 466/4885HPGD 1366/4885
US-20150289505-A1 HERBICIDE COMPOSITION DDT, DHFR, DERL1 MEN1 3856/4885KMT2A 1181/4885HPGD 585/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.