SCHEMBL15958348

SCHEMBL15958348

C=Cc1ccc(COC(=O)C(CN)C(=O)OCc2ccc(C=C)cc2)cc1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
TAS1R3 Q7RTX0 2/20 0.36
TAS1R1 Q7RTX1 2/20 0.36
LTA4H P09960 1/20 0.36
LAP3 P28838 1/20 0.36
ALDH1A1 P00352 3/20 0.35
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
CA12 O43570 1/20 0.35
AKR1B10 O60218 1/20 0.35
AKR1B1 P15121 1/20 0.35
CA4 P22748 1/20 0.35
CA6 P23280 1/20 0.35
CA5A P35218 1/20 0.35
CA7 P43166 1/20 0.35
CA9 Q16790 1/20 0.35
CA14 Q9ULX7 1/20 0.35
CA5B Q9Y2D0 1/20 0.35
LMNA P02545 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15958349 0.89 LMNA (0.37) LTA4HLAP3ALDH1A1CA12AKR1B10
SCHEMBL15958345 0.88 CA1 (0.37) MEN1KMT2ATAS1R3TAS1R1LTA4H
SCHEMBL16022460 0.85 LTA4H (0.40) MEN1KMT2ATAS1R3TAS1R1LTA4H
SCHEMBL15292568 0.84 MEN1 (0.41) MEN1KMT2ATAS1R3TAS1R1ALDH1A1
SCHEMBL15958347 0.82 PTGS2 (0.38) MEN1KMT2ALTA4HLAP3ALDH1A1
SCHEMBL15292563 0.81 TAS1R3 (0.48) MEN1KMT2ATAS1R3TAS1R1ALDH1A1
SCHEMBL21534581 0.81 TAS1R3 (0.42) MEN1KMT2ATAS1R3TAS1R1LTA4H
SCHEMBL15907712 0.80 TAS1R3 (0.43) MEN1KMT2ATAS1R3TAS1R1ALDH1A1
SCHEMBL15958350 0.79 LMNA (0.35) LTA4HLAP3ALDH1A1CA12AKR1B10
SCHEMBL14944204 0.78 AKR1B10 (0.42) MEN1KMT2ATAS1R3TAS1R1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8951701-B2 Composition for forming charge transporting film, electrophotographic photoreceptor, process cartridge, and image forming apparatus FUJI XEROX CO., LTD. (JP) 2015-02-10 US disclosed
US-20140321882-A1 COMPOSITION FOR FORMING CHARGE TRANSPORTING FILM, ELECTROPHOTOGRAPHIC PHOTORECEPTOR, PROCESS CARTRIDGE, AND IMAGE FORMING APPARATUS FUJI XEROX CO., LTD. (JP) 2014-10-30 US disclosed
US-8808952-B2 Composition for forming charge transporting film, electrophotographic photoreceptor, process cartridge, and image forming apparatus FUJI XEROX CO., LTD. (JP) 2014-08-19 US disclosed