SCHEMBL15959624

SCHEMBL15959624

CCCCCCCCC1CC1CCCCCCCCO

nearest known ligand 0.60

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.60
ALDH1A1 P00352 3/20 0.59
LMNA P02545 2/20 0.59
HSD17B10 Q99714 1/20 0.59
MEN1 O00255 1/20 0.59
KMT2A Q03164 1/20 0.59
TSHR P16473 1/20 0.59
SMN1; SMN2 Q16637 1/20 0.55
EPHX1 P07099 1/20 0.39
GBA1 P04062 6/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11913449 1.00 ALOX5 (0.60) ALOX5ALDH1A1LMNAHSD17B10MEN1
SCHEMBL24599953 1.00 ALOX5 (0.60) ALOX5ALDH1A1LMNAHSD17B10MEN1
SCHEMBL13060191 1.00 ALOX5 (0.60) ALOX5ALDH1A1LMNAHSD17B10MEN1
SCHEMBL12036601 1.00 ALOX5 (0.60) ALOX5ALDH1A1LMNAHSD17B10MEN1
SCHEMBL15259625 0.94 ALOX5 (0.55) ALOX5ALDH1A1LMNAHSD17B10MEN1
SCHEMBL15259577 0.94 ALOX5 (0.55) ALOX5ALDH1A1LMNAHSD17B10MEN1
SCHEMBL15259624 0.94 ALOX5 (0.55) ALOX5ALDH1A1LMNAHSD17B10MEN1
SCHEMBL15259595 0.94 ALOX5 (0.55) ALOX5ALDH1A1LMNAHSD17B10MEN1
SCHEMBL15259592 0.94 ALOX5 (0.55) ALOX5ALDH1A1LMNAHSD17B10MEN1
SCHEMBL16656319 0.94 ALOX5 (0.55) ALOX5ALDH1A1LMNAHSD17B10MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117441047-A Treatment agent for synthetic fibers, and method for treating synthetic fibers 竹本油脂株式会社 2024-01-23 CN disclosed
US-11826345-B2 Dosing regimens of PKC activators Synaptogenix, Inc. (US) 2023-11-28 US disclosed
US-11826345-B2 Dosing regimens of PKC activators Synaptogenix, Inc. (US) 2023-11-28 US disclosed
US-20230000943-A1 METHOD OF INDUCING SYNAPTOGENESIS BY ADMINISTERING ANGIOTENSIN AND ANALOGUES THEREOF Synaptogenix, Inc. (US) 2023-01-05 US disclosed
WO-2022219889-A1 TREATMENT AGENT FOR SYNTHETIC FIBERS, SYNTHETIC FIBERS, AND TREATMENT METHOD FOR SYNTHETIC FIBERS 竹本油脂株式会社 2022-10-20 WO disclosed
US-20220265857-A1 COMPOSITIONS AND METHODS FOR DELIVERY OF AGENTS MODERNATX, INC. (US) 2022-08-25 US disclosed
EP-3386484-B1 COMPOSITIONS AND METHODS FOR DELIVERY OF THERAPEUTIC AGENTS MODERNATX INC (US) 2022-03-30 EP disclosed
US-11285222-B2 Compositions and methods for delivery of agents MODERNATX, INC. (US) 2022-03-29 US disclosed
US-20210023048-A1 DOSING REGIMENS OF PKC ACTIVATORS COGNITIVE RESEARCH ENTERPRISES, INC. (US) 2021-01-28 US disclosed
US-20200206362-A1 COMPOSITIONS AND METHODS FOR DELIVERY OF AGENTS Moderna TX, Inc. (US) 2020-07-02 US disclosed
US-20180147298-A1 COMPOSITIONS AND METHODS FOR DELIVERY OF AGENTS MODERNATX, INC. (US) 2018-05-31 US disclosed
US-20180028664-A1 COMPOSITIONS AND METHODS FOR DELIVERY OF AGENTS MODERNATX, INC. (US) 2018-02-01 US disclosed
US-20180028664-A1 COMPOSITIONS AND METHODS FOR DELIVERY OF AGENTS MODERNATX, INC. (US) 2018-02-01 US disclosed
US-20180028664-A1 COMPOSITIONS AND METHODS FOR DELIVERY OF AGENTS MODERNATX, INC. (US) 2018-02-01 US disclosed
WO-2017099823-A1 COMPOSITIONS AND METHODS FOR DELIVERY OF THERAPEUTIC AGENTS MODERNATX, INC. (US) 2017-06-15 WO disclosed
WO-2017099823-A1 COMPOSITIONS AND METHODS FOR DELIVERY OF THERAPEUTIC AGENTS MODERNATX, INC. (US) 2017-06-15 WO disclosed
US-20140315990-A1 PKC ACTIVATORS AND COMBINATIONS THEREOF COGNITIVE RESEARCH ENTERPRISES, INC. 2014-10-23 US disclosed
US-20140315990-A1 PKC ACTIVATORS AND COMBINATIONS THEREOF COGNITIVE RESEARCH ENTERPRISES, INC. 2014-10-23 US disclosed
US-20140235496-A1 STIMULUS-ELICITED GENOMIC PROFILE MARKERS OF A NEURODEGENERATIVE CONDITION BLANCHETTE ROCKEFELLER NEUROSCIENCES DRIVE (US) 2014-08-21 US disclosed
US-20140235496-A1 STIMULUS-ELICITED GENOMIC PROFILE MARKERS OF A NEURODEGENERATIVE CONDITION BLANCHETTE ROCKEFELLER NEUROSCIENCES DRIVE (US) 2014-08-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200206362-A1 COMPOSITIONS AND METHODS FOR DELIVERY OF AGENTS HDLBP, APOB, TSG101 ALOX5 3206/4885ALDH1A1 3952/4885LMNA 248/4885
US-11285222-B2 Compositions and methods for delivery of agents HDLBP, APOB, TSG101 ALOX5 3206/4885ALDH1A1 3952/4885LMNA 248/4885
US-20230000943-A1 METHOD OF INDUCING SYNAPTOGENESIS BY ADMINISTERING ANGIOTENSIN AND ANALOGUES THEREOF GAP43, SNAP29, SYNGR2 ALOX5 443/4885ALDH1A1 4331/4885LMNA 2577/4885
US-20210023048-A1 DOSING REGIMENS OF PKC ACTIVATORS PRKCA, PRKCH, PRKCQ ALOX5 2400/4885ALDH1A1 4374/4885LMNA 2436/4885
US-20220265857-A1 COMPOSITIONS AND METHODS FOR DELIVERY OF AGENTS HDLBP, APOB, TSG101 ALOX5 3206/4885ALDH1A1 3952/4885LMNA 248/4885
US-20180147298-A1 COMPOSITIONS AND METHODS FOR DELIVERY OF AGENTS HDLBP, APOB, TSG101 ALOX5 3206/4885ALDH1A1 3952/4885LMNA 248/4885
US-20140315990-A1 PKC ACTIVATORS AND COMBINATIONS THEREOF PRKCH, PRKCB, PRKCA ALOX5 3192/4885ALDH1A1 4622/4885LMNA 1261/4885
US-20180028664-A1 COMPOSITIONS AND METHODS FOR DELIVERY OF AGENTS HDLBP, APOB, TSG101 ALOX5 3206/4885ALDH1A1 3952/4885LMNA 248/4885
US-11826345-B2 Dosing regimens of PKC activators PRKCA, PRKCH, PRKCQ ALOX5 2400/4885ALDH1A1 4374/4885LMNA 2436/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.