Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.54 |
| ▸ | CTNNB1 | P35222 | 2/20 | 0.53 |
| ▸ | WNT3A | P56704 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.49 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26090283 | 0.86 | CTNNB1 (0.58) | MEN1KMT2AHPGDMAPTCTNNB1 | |
| SCHEMBL3948073 | 0.86 | MEN1 (0.60) | MEN1KMT2AKDM4ESMN1; SMN2HPGD | |
| SCHEMBL15965424 | 0.86 | CTNNB1 (0.53) | MEN1KMT2AKDM4ESMN1; SMN2RAB9A | |
| SCHEMBL29578705 | 0.85 | MEN1 (0.73) | MEN1KMT2AKDM4ESMN1; SMN2HPGD | |
| SCHEMBL515746 | 0.85 | MEN1 (0.73) | MEN1KMT2AKDM4ESMN1; SMN2HPGD | |
| SCHEMBL11335265 | 0.84 | MAPT (0.55) | MEN1KMT2AHPGDMAPTCYP1A2 | |
| SCHEMBL12937549 | 0.84 | CTNNB1 (0.51) | MEN1KMT2AKDM4ERAB9AMAPT | |
| SCHEMBL15965411 | 0.84 | GSK3B (0.56) | MEN1KMT2ARAB9AMAPTCYP1A2 | |
| SCHEMBL12378894 | 0.82 | MEN1 (0.68) | MEN1KMT2AKDM4ESMN1; SMN2MAPT | |
| SCHEMBL1396833 | 0.82 | MEN1 (0.68) | MEN1KMT2AKDM4ESMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9359391-B2 | Selective C—O bond cleavage of oxidized lignin and lignin-type materials into simple aromatic compounds | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2016-06-07 | — | — | US | disclosed |
| US-20150259368-A1 | SELECTIVE C-O BOND CLEAVAGE OF OXIDIZED LIGNIN AND LIGNIN-TYPE MATERIALS INTO SIMPLE AROMATIC COMPOUNDS | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2015-09-17 | — | — | US | disclosed |
| US-8969534-B2 | Selective aerobic alcohol oxidation method for conversion of lignin into simple aromatic compounds | Wisconsin Alumni Research Foundataion (US) | 2015-03-03 | — | — | US | disclosed |
| US-20140235838-A1 | SELECTIVE AEROBIC ALCOHOL OXIDATION METHOD FOR CONVERSION OF LIGNIN INTO SIMPLE AROMATIC COMPOUNDS | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2014-08-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150259368-A1 | SELECTIVE C-O BOND CLEAVAGE OF OXIDIZED LIGNIN AND LIGNIN-TYPE MATERIALS INTO SIMPLE AROMATIC COMPOUNDS | AOC2, AOX1, AOC3 | MEN1 4825/4885KMT2A 951/4885KDM4E 184/4885 |
| US-20140235838-A1 | SELECTIVE AEROBIC ALCOHOL OXIDATION METHOD FOR CONVERSION OF LIGNIN INTO SIMPLE AROMATIC COMPOUNDS | AOX1, SOD1, NOX4 | MEN1 4458/4885KMT2A 1052/4885KDM4E 715/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.