Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | CRHR1 | P34998 | 6/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | AHR | P35869 | 1/20 | 0.41 |
| ▸ | S100A4 | P26447 | 2/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.41 |
| ▸ | CCR2 | P41597 | 1/20 | 0.37 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.37 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.37 |
| ▸ | ITGAL | P20701 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24588651 | 0.79 | RAB9A (0.56) | NPC1RAB9AHPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL8779862 | 0.78 | ITGB2 (0.50) | NPC1RAB9AHPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL28830542 | 0.76 | CCR2 (0.47) | HPGDALDH1A1CYP1A2CYP2C19S100A4 | |
| SCHEMBL464507 | 0.74 | AHR (0.64) | RAB9AALDH1A1KDM4ECRHR1AHR | |
| SCHEMBL29624840 | 0.74 | AHR (0.64) | RAB9AALDH1A1KDM4ECRHR1AHR | |
| SCHEMBL24030824 | 0.74 | CRHR1 (0.45) | NPC1RAB9AHPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL28607196 | 0.72 | S100A4 (0.68) | ALDH1A1SMN1; SMN2AHRS100A4TP53 | |
| SCHEMBL15440754 | 0.71 | AHR (0.45) | RAB9AHPGDALDH1A1KDM4ECRHR1 | |
| SCHEMBL3787206 | 0.71 | CCR2 (0.46) | NPC1RAB9AHPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL4446831 | 0.71 | TP53 (0.57) | RAB9AALDH1A1KDM4EAHRS100A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140230871-A1 | THERMOELECTRIC CONVERSION MATERIAL AND THERMOELECTRIC CONVERSION ELEMENT | FUJIFILM CORPORATION (JP) | 2014-08-21 | — | — | US | disclosed |