SCHEMBL1596586

SCHEMBL1596586

O=S(=O)(Br)c1ccc(CCl)cc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 14/20 0.45
CA1 P00915 12/20 0.45
CA9 Q16790 7/20 0.37
CA12 O43570 6/20 0.37
CA7 P43166 6/20 0.37
CA4 P22748 4/20 0.37
CA6 P23280 4/20 0.37
CA5A P35218 4/20 0.37
CA14 Q9ULX7 4/20 0.37
CA5B Q9Y2D0 4/20 0.37
MAPT P10636 1/20 0.35
PSIP1 O75475 1/20 0.34
PLCG1 P19174 1/20 0.33
F2 P00734 1/20 0.33
TP53 P04637 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP2D6 P10635 1/20 0.33
TSHR P16473 1/20 0.33
TMPRSS4 Q9NRS4 1/20 0.33
KMT2A Q03164 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3539406 0.80 CYP3A4 (0.52) CA2CA1CA9CA12CA7
SCHEMBL8779885 0.79 CA2 (0.41) CA2CA1CA9CA12CA7
SCHEMBL8996770 0.78 TSHR (0.42) CA2CA1CA9CA12CA7
SCHEMBL396619 0.78 ALDH1A1 (0.50) CA2CA1CA9CA12CA7
SCHEMBL4125638 0.78 CA2 (0.46) CA2CA1CA9CA12CA7
SCHEMBL1596533 0.77 CA2 (0.42) CA2CA1CA9CA12CA7
SCHEMBL14830747 0.76 CA2 (0.48) CA2CA1CA9CA12CA7
SCHEMBL3386871 0.76 LMNA (0.52) CA2CA1CA9CA12CA7
SCHEMBL11205634 0.76 F2 (0.57) CA2CA1CA9CA12CA7
SCHEMBL1595559 0.76 CA2 (0.45) CA2CA1CA9CA12CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8710165-B2 Multibranched polymer and method for producing the same NIPPON SODA CO., LTD. (JP) 2014-04-29 US disclosed
CN-101001887-B Multi-branched polymer and method for producing same NIPPON SODA CO.,LTD. (JP) 2012-02-08 CN disclosed
US-20110152388-A1 Multibranched polymer and method for producing the same NIPPON SODA CO., LTD. (JP) 2011-06-23 US disclosed
US-7919570-B2 narrowly dispersed; controlled molecular weight; ionic conductivity, shape stability; battery adhesive or binder; 1,1,2,2-tetrakis(4-hydroxyphenyl)ethane or pentaerythritol reacted with bromoisobutyroyl bromide for core; living radical polymerization of acrylate or a styrene at halogen atoms as the arms NIPPON SODA CO., LTD. (JP) 2011-04-05 US disclosed
US-20080214685-A1 Multibrached Polymer and Method for Producing the Same NIPPON SODA CO., LTD. (JP) 2008-09-04 US disclosed
CN-101001887-A Multi-branched polymer and method for producing same NIPPON SODA CO (JP) 2007-07-18 CN disclosed