Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 11/20 | 0.38 |
| ▸ | CA1 | P00915 | 9/20 | 0.38 |
| ▸ | CA9 | Q16790 | 7/20 | 0.38 |
| ▸ | CA12 | O43570 | 6/20 | 0.38 |
| ▸ | CA7 | P43166 | 5/20 | 0.38 |
| ▸ | CA4 | P22748 | 4/20 | 0.38 |
| ▸ | CA6 | P23280 | 4/20 | 0.38 |
| ▸ | CA5A | P35218 | 4/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.38 |
| ▸ | CA5B | Q9Y2D0 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.35 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.34 |
| ▸ | F2 | P00734 | 2/20 | 0.34 |
| ▸ | TMPRSS4 | Q9NRS4 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1148233 | 0.82 | HTR6 (0.47) | TSHRTRPA1ALDH1A1CES2CES1 | |
| SCHEMBL8779885 | 0.81 | CA2 (0.41) | TSHRALDH1A1CA2CA1CA9 | |
| SCHEMBL2881343 | 0.78 | TRPA1 (0.40) | TSHRTRPA1ALDH1A1CES2CES1 | |
| SCHEMBL27532571 | 0.78 | CA2 (0.64) | TSHRCA2CA1CA9CA12 | |
| SCHEMBL297518 | 0.78 | ALDH1A1 (0.48) | TSHRTRPA1ALDH1A1CES2CES1 | |
| SCHEMBL185587 | 0.78 | CA2 (0.64) | TSHRCA2CA1CA9CA12 | |
| SCHEMBL7769099 | 0.78 | F2 (0.57) | TSHRTRPA1ALDH1A1CES2CES1 | |
| SCHEMBL240747 | 0.78 | ENPP2 (0.50) | TSHRTRPA1ALDH1A1CA2 | |
| SCHEMBL819787 | 0.78 | LMNA (0.52) | TSHRTRPA1ALDH1A1CES2CES1 | |
| SCHEMBL1596586 | 0.78 | CA2 (0.45) | TSHRCA2CA1CA9CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0404261-B1 | Poly(alkenyl substituted aromatic) and elastomer containing polymer compositions and process for their preparation | SHELL INT RESEARCH (NL) | 1996-08-28 | — | — | EP | claimed |
| US-5079268-A | POLY(ALKENYL SUBSTITUTED AROMATIC) AND ELASTOMER CONTAINING POLYMER COMPOSITIONS AND PROCESS FOR THEIR PREPARATION | SHELL RESEARCH LIMITED (GB) | 1992-01-07 | — | — | US | claimed |
| EP-0404261-B1 | Poly(alkenyl substituted aromatic) and elastomer containing polymer compositions and process for their preparation | SHELL INT RESEARCH (NL) | 1996-08-28 | — | — | EP | disclosed |
| US-5079268-A | POLY(ALKENYL SUBSTITUTED AROMATIC) AND ELASTOMER CONTAINING POLYMER COMPOSITIONS AND PROCESS FOR THEIR PREPARATION | SHELL RESEARCH LIMITED (GB) | 1992-01-07 | — | — | US | disclosed |
| EP-0404261-A2 | Poly(alkenyl substituted aromatic) and elastomer containing polymer compositions and process for their preparation | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1990-12-27 | — | — | EP | disclosed |