Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 12/20 | 0.40 |
| ▸ | RIPK1 | Q13546 | 3/20 | 0.40 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16004271 | 0.84 | RIPK1 (0.45) | PIK3CARIPK1AOC3MEN1KMT2A | |
| SCHEMBL16004232 | 0.83 | PIK3CA (0.49) | PIK3CARIPK1AOC3HPGD | |
| SCHEMBL16004283 | 0.81 | CREBBP (0.52) | CREBBP | |
| SCHEMBL16004052 | 0.78 | PIK3CA (0.52) | PIK3CARIPK1AOC3HPGD | |
| SCHEMBL16004055 | 0.77 | PIK3CA (0.49) | PIK3CARIPK1MEN1KMT2A | |
| SCHEMBL16004054 | 0.77 | PIK3CA (0.49) | PIK3CARIPK1AOC3MEN1KMT2A | |
| SCHEMBL16004274 | 0.77 | RIPK1 (0.46) | PIK3CARIPK1MEN1KMT2AHPGD | |
| SCHEMBL16004053 | 0.77 | RIPK1 (0.49) | PIK3CARIPK1 | |
| SCHEMBL16004269 | 0.75 | RIPK1 (0.46) | PIK3CARIPK1MEN1KMT2AHPGD | |
| SCHEMBL16004059 | 0.75 | HPGD (0.47) | PIK3CAKMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014133414-A2 | HETEROCYCLIC TGR5 BILE ACID RECEPTOR AGONISTS, PHARMACEUTICAL COMPOSITION, METHODS FOR THE PRODUCTION AND USE THEREOF | АЛЛА ХЕМ ЛЛС (US) | 2014-09-04 | — | — | WO | disclosed |