Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CREBBP | Q92793 | 20/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16004285 | 0.90 | CREBBP (0.54) | CREBBP | |
| SCHEMBL16004271 | 0.88 | RIPK1 (0.45) | CREBBP | |
| SCHEMBL16004243 | 0.81 | PIK3CA (0.40) | CREBBP | |
| SCHEMBL16004274 | 0.81 | RIPK1 (0.46) | CREBBP | |
| SCHEMBL16004232 | 0.79 | PIK3CA (0.49) | — | |
| SCHEMBL16004269 | 0.79 | RIPK1 (0.46) | CREBBP | |
| SCHEMBL16003958 | 0.78 | CREBBP (0.56) | CREBBP | |
| SCHEMBL16004249 | 0.78 | RIPK1 (0.41) | CREBBP | |
| SCHEMBL16004278 | 0.78 | GPR142 (0.59) | — | |
| SCHEMBL16004070 | 0.77 | GPR142 (0.49) | CREBBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014133414-A2 | HETEROCYCLIC TGR5 BILE ACID RECEPTOR AGONISTS, PHARMACEUTICAL COMPOSITION, METHODS FOR THE PRODUCTION AND USE THEREOF | АЛЛА ХЕМ ЛЛС (US) | 2014-09-04 | — | — | WO | disclosed |