Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 3/20 | 0.41 |
| ▸ | CREBBP | Q92793 | 13/20 | 0.41 |
| ▸ | GPR142 | Q7Z601 | 1/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16004274 | 0.88 | RIPK1 (0.46) | RIPK1CREBBPGPR142PIK3CAMEN1 | |
| SCHEMBL16004236 | 0.87 | KDM4E (0.43) | RIPK1CREBBPGPR142PIK3CAMEN1 | |
| SCHEMBL16004285 | 0.87 | CREBBP (0.54) | CREBBP | |
| SCHEMBL16004269 | 0.87 | RIPK1 (0.46) | RIPK1CREBBPGPR142PIK3CAMEN1 | |
| SCHEMBL16004233 | 0.84 | GPR142 (0.47) | RIPK1GPR142PIK3CAKMT2A | |
| SCHEMBL16004244 | 0.84 | GPR142 (0.37) | RIPK1CREBBPGPR142MEN1KMT2A | |
| SCHEMBL16004052 | 0.81 | PIK3CA (0.52) | RIPK1PIK3CA | |
| SCHEMBL16004278 | 0.81 | GPR142 (0.59) | GPR142 | |
| SCHEMBL16004055 | 0.80 | PIK3CA (0.49) | RIPK1GPR142PIK3CAMEN1KMT2A | |
| SCHEMBL16004054 | 0.80 | PIK3CA (0.49) | RIPK1CREBBPPIK3CAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014133414-A2 | HETEROCYCLIC TGR5 BILE ACID RECEPTOR AGONISTS, PHARMACEUTICAL COMPOSITION, METHODS FOR THE PRODUCTION AND USE THEREOF | АЛЛА ХЕМ ЛЛС (US) | 2014-09-04 | — | — | WO | disclosed |