SCHEMBL160101

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL165921	0.83	CA12 (0.42)	L3MBTL1KDM4EALDH1A1LMNAMAPT
	SCHEMBL164287	0.77	CYP1A2 (0.53)	GABRA1GABRG2GABRB3GABRA5GABRA3
	SCHEMBL158283	0.76	ALDH1A1 (0.45)	L3MBTL1KDM4EALDH1A1LMNAGLA
	SCHEMBL162103	0.74	MRGPRX4 (0.43)	L3MBTL1KDM4EALDH1A1GLAGAA
	SCHEMBL163670	0.74	ALDH1A1 (0.45)	GABRA1GABRG2GABRB3GABRA5GABRA3
	SCHEMBL15204499	0.72	GABRA1 (0.40)	GABRA1GABRG2GABRB3GABRA5GABRA3
	SCHEMBL161243	0.72	GABRA1 (0.42)	GABRA1GABRG2GABRB3GABRA5GABRA3
	SCHEMBL162976	0.72	L3MBTL1 (0.49)	L3MBTL1KDM4EALDH1A1LMNAHPGD
	SCHEMBL162375	0.72	CA12 (0.41)	GABRA1GABRG2GABRB3GABRA5GABRA3
	SCHEMBL165489	0.71	GABRA1 (0.44)	GABRA1GABRG2GABRB3GABRA5GABRA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.