SCHEMBL162976

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL163670	0.90	ALDH1A1 (0.45)	L3MBTL1TSHRESR1LMNACYP1A2
	SCHEMBL164287	0.83	CYP1A2 (0.53)	TSHRESR1LMNACYP1A2CYP2C19
	SCHEMBL8405192	0.76	MAPT (0.64)	L3MBTL1TSHRLMNACYP1A2SMN1; SMN2
	SCHEMBL158283	0.76	ALDH1A1 (0.45)	L3MBTL1TSHRLMNACYP1A2SMN1; SMN2
	SCHEMBL162103	0.74	MRGPRX4 (0.43)	L3MBTL1CYP1A2CYP2C19SMN1; SMN2MAPK1
	SCHEMBL3885590	0.73	CYP1A2 (0.68)	L3MBTL1TSHRESR1LMNACYP1A2
	SCHEMBL8405202	0.73	L3MBTL1 (0.67)	L3MBTL1TSHRESR1LMNACYP1A2
	SCHEMBL31277364	0.72	ESR1 (0.56)	L3MBTL1TSHRESR1LMNACYP1A2
	SCHEMBL160101	0.72	GABRA1 (0.42)	L3MBTL1LMNACYP1A2CYP2C19SMN1; SMN2
	SCHEMBL162551	0.72	LMNA (0.49)	L3MBTL1TSHRESR1LMNACYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.