Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 18/20 | 0.54 |
| ▸ | EPAS1 | Q99814 | 18/20 | 0.54 |
| ▸ | COXFA4 | O00483 | 1/20 | 0.45 |
| ▸ | EP300 | Q09472 | 1/20 | 0.44 |
| ▸ | TLR3 | O15455 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12315461 | 0.80 | COXFA4 (0.62) | HIF1AEPAS1COXFA4EP300 | |
| SCHEMBL9032911 | 0.80 | HIF1A (0.54) | HIF1AEPAS1TLR3 | |
| SCHEMBL5868243 | 0.80 | HIF1A (0.54) | HIF1AEPAS1COXFA4TLR3 | |
| SCHEMBL9032078 | 0.78 | HIF1A (0.53) | HIF1AEPAS1COXFA4EP300 | |
| Eulatachromene SCHEMBL9033640 | 0.78 | HIF1A (0.53) | HIF1AEPAS1COXFA4TLR3 | |
| SCHEMBL30523641 | 0.78 | HIF1A (0.53) | HIF1AEPAS1TLR3 | |
| SCHEMBL507142 | 0.78 | HIF1A (0.53) | HIF1AEPAS1TLR3 | |
| SCHEMBL17781626 | 0.78 | HIF1A (0.48) | HIF1AEPAS1 | |
| SCHEMBL5808068 | 0.78 | HIF1A (0.48) | HIF1AEPAS1COXFA4 | |
| SCHEMBL2827569 | 0.76 | HIF1A (0.54) | HIF1AEPAS1COXFA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9763444-B2 | Compositions and methods for repelling blood-sucking and biting insects, ticks and mites | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) | 2017-09-19 | — | — | US | disclosed |
| US-20160165886-A1 | Compositions and Methods For Repelling Blood-Sucking and Biting Insects, Ticks and Mites | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF AGRICULTURE | 2016-06-16 | — | — | US | disclosed |
| WO-2014137811-A1 | COMPOSITIONS AND METHODS FOR REPELLING BLOOD-SUCKING AND BITING INSECTS, TICKS AND MITES | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) | 2014-09-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160165886-A1 | Compositions and Methods For Repelling Blood-Sucking and Biting Insects, Ticks and Mites | AMY1A, AMY2A, TRHDE | HIF1A 4440/4885EPAS1 4337/4885COXFA4 3697/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.