Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDAH1 | O94760 | 1/20 | 0.31 |
| ▸ | NOS1 | P29475 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | APEX1 | P27695 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | NOS2 | P35228 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28861616 | 0.86 | SGPL1 (0.34) | NOS2 | |
| SCHEMBL15045488 | 0.83 | CA2 (0.47) | DDAH1 | |
| SCHEMBL19555534 | 0.79 | CA1 (0.36) | TSHRNFKB1 | |
| SCHEMBL25317082 | 0.76 | CA2 (0.58) | DDAH1NOS1CYP2C19NOS2 | |
| SCHEMBL18088373 | 0.76 | TSHR (0.48) | CYP1A2TSHRNFKB1CYP2C19 | |
| SCHEMBL28601410 | 0.74 | — | — | |
| SCHEMBL28950362 | 0.73 | KDM4E (0.47) | — | |
| SCHEMBL24295447 | 0.73 | CTSL (0.34) | DDAH1NOS1 | |
| SCHEMBL15888955 | 0.72 | NOS2 (0.43) | DDAH1NOS1CYP1A2GLATSHR | |
| SCHEMBL17074958 | 0.70 | ZDHHC20 (0.49) | DDAH1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2964224-A1 | POLYMER CONJUGATE FOR DELIVERY OF A BIOACTIVE AGENT | Polyactiva Pty Ltd (AU) | 2016-01-13 | — | — | EP | disclosed |
| WO-2014134689-A1 | POLYMER CONJUGATE FOR DELIVERY OF A BIOACTIVE AGENT | POLYACTIVA PTY LTD (AU) | 2014-09-12 | — | — | WO | disclosed |