Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 1/20 | 0.34 |
| ▸ | CTSB | P07858 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 3/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.32 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.32 |
| ▸ | PADI1 | Q9ULC6 | 2/20 | 0.32 |
| ▸ | PADI4 | Q9UM07 | 2/20 | 0.32 |
| ▸ | PADI2 | Q9Y2J8 | 2/20 | 0.32 |
| ▸ | PADI6 | Q6TGC4 | 1/20 | 0.32 |
| ▸ | PADI3 | Q9ULW8 | 1/20 | 0.32 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.31 |
| ▸ | NOS1 | P29475 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23589784 | 0.81 | CTSL (0.36) | CTSLCTSBCHRM2CHRM4CHRM1 | |
| SCHEMBL22375469 | 0.79 | FOLH1 (0.33) | CHRM2CHRM4CHRM1 | |
| SCHEMBL22375471 | 0.78 | FOLH1 (0.32) | — | |
| SCHEMBL19475787 | 0.77 | CA2 (0.50) | CA1CA2 | |
| SCHEMBL25317082 | 0.75 | CA2 (0.58) | DDAH1NOS1CA1CA2 | |
| Hydrochloric Acid SCHEMBL8527464 | 0.74 | FOLH1 (0.38) | CA1CA2 | |
| SCHEMBL31520085 | 0.74 | MMP3 (0.44) | CA1CA2 | |
| SCHEMBL31520094 | 0.74 | MMP3 (0.44) | CA1CA2 | |
| SCHEMBL8976019 | 0.74 | MMP3 (0.35) | CA1CA2 | |
| SCHEMBL15834023 | 0.74 | FOLH1 (0.45) | CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220119465-A1 | DUAL IL-2R AND IL-7R BINDING COMPOUNDS | JEFFREY W. AND CHRISTINA R. BIRD TRUST U/A/D | 2022-04-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220119465-A1 | DUAL IL-2R AND IL-7R BINDING COMPOUNDS | IL2RA, IL2, IL23R | CTSL 1444/4885CTSB 1047/4885CHRM2 4190/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.