SCHEMBL16019355

SCHEMBL16019355

CC(C)(C)C(C)(C)c1ccccc1S(=O)(=O)C(F)(F)F

nearest known ligand 0.40

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
HSD11B1 P28845 3/20 0.36
SLC22A12 Q96S37 9/20 0.36
CA2 P00918 2/20 0.35
CA1 P00915 1/20 0.34
CA5A P35218 1/20 0.34
CA9 Q16790 1/20 0.34
ALDH1A1 P00352 1/20 0.33
TSHR P16473 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
NFE2L2 Q16236 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10180608 0.84 HSD11B1 (0.49) MEN1KMT2AHSD11B1SLC22A12CA2
SCHEMBL6929900 0.79 CA2 (0.44) MEN1KMT2AHSD11B1SLC22A12CA2
SCHEMBL10179703 0.78 MEN1 (0.38) MEN1KMT2AHSD11B1SLC22A12CA2
SCHEMBL14349353 0.78 BCAT2 (0.37) MEN1KMT2AHSD11B1ALDH1A1TSHR
SCHEMBL16019344 0.74 PSIP1 (0.43) MEN1KMT2AHSD11B1ALDH1A1TDP1
SCHEMBL9965492 0.74 HSD11B1 (0.47) MEN1KMT2AHSD11B1CA2ALDH1A1
SCHEMBL16019345 0.73 ADRA2A (0.35) MEN1KMT2AHSD11B1SLC22A12
SCHEMBL856017 0.72 KMT2A (0.55) MEN1KMT2AHSD11B1SLC22A12ALDH1A1
SCHEMBL945367 0.71 MEN1 (0.40) MEN1KMT2AHSD11B1SLC22A12CA2
SCHEMBL6264610 0.71 CA2 (0.43) MEN1KMT2ACA2CA1CA5A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9693556-B2 Herbicidal pyridazinone derivatives SYNGENTA LIMITED (GB) 2017-07-04 US disclosed
US-9693556-B2 Herbicidal pyridazinone derivatives SYNGENTA LIMITED (GB) 2017-07-04 US disclosed
US-20140256546-A1 HERBICIDAL PYRIDAZINONE DERIVATIVES SYNGENTA LIMITED (GB) 2014-09-11 US disclosed
US-20140256546-A1 HERBICIDAL PYRIDAZINONE DERIVATIVES SYNGENTA LIMITED (GB) 2014-09-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140256546-A1 HERBICIDAL PYRIDAZINONE DERIVATIVES PRDX6, PRDX1, CBR3 MEN1 4302/4885KMT2A 1922/4885HSD11B1 1661/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.