Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV4 | Q9HBA0 | 2/20 | 0.43 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.41 |
| ▸ | EPAS1 | Q99814 | 3/20 | 0.36 |
| ▸ | TBXA2R | P21731 | 6/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | ALPL | P05186 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 2/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18469731 | 0.86 | TRPV4 (0.45) | TRPV4RAD51EPAS1TBXA2RPTGS2 | |
| SCHEMBL10164103 | 0.75 | RAD51 (0.45) | TRPV4RAD51EPAS1PTGS2ALPL | |
| SCHEMBL16019385 | 0.75 | SMN1; SMN2 (0.55) | PTGS2 | |
| SCHEMBL125367 | 0.75 | RAD51 (0.45) | TRPV4RAD51EPAS1TBXA2RPTGS2 | |
| SCHEMBL13211338 | 0.75 | SMN1; SMN2 (0.59) | TRPV4RAD51EPAS1ALPL | |
| SCHEMBL16019362 | 0.74 | CCR2 (0.41) | TRPV4 | |
| SCHEMBL15412234 | 0.74 | ACLY (0.49) | TRPV4RAD51EPAS1TBXA2RPTGS2 | |
| SCHEMBL12560333 | 0.74 | VCAM1 (0.46) | TRPV4RAD51EPAS1PTGS2ELANE | |
| SCHEMBL8255487 | 0.74 | RAD51 (0.44) | TRPV4RAD51EPAS1PTGS2CA1 | |
| SCHEMBL16019376 | 0.74 | SMN1; SMN2 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9693556-B2 | Herbicidal pyridazinone derivatives | SYNGENTA LIMITED (GB) | 2017-07-04 | — | — | US | disclosed |
| US-9693556-B2 | Herbicidal pyridazinone derivatives | SYNGENTA LIMITED (GB) | 2017-07-04 | — | — | US | disclosed |
| US-20140256546-A1 | HERBICIDAL PYRIDAZINONE DERIVATIVES | SYNGENTA LIMITED (GB) | 2014-09-11 | — | — | US | disclosed |
| US-20140256546-A1 | HERBICIDAL PYRIDAZINONE DERIVATIVES | SYNGENTA LIMITED (GB) | 2014-09-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140256546-A1 | HERBICIDAL PYRIDAZINONE DERIVATIVES | PRDX6, PRDX1, CBR3 | TRPV4 3758/4885RAD51 3713/4885EPAS1 4565/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.