Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AXL | P30530 | 9/20 | 0.37 |
| ▸ | MET | P08581 | 6/20 | 0.37 |
| ▸ | MERTK | Q12866 | 6/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.33 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17427479 | 0.85 | POLB (0.47) | AXLMETLMNANPC1ALDH1A1 | |
| SCHEMBL17427475 | 0.82 | TYRO3 (0.41) | AXLMETMERTKTYRO3RAB9A | |
| SCHEMBL17427487 | 0.70 | RIPK1 (0.35) | METLMNAGAA | |
| SCHEMBL16022005 | 0.69 | POLB (0.44) | METLMNANPC1ALDH1A1RAB9A | |
| SCHEMBL16022003 | 0.67 | HCAR1 (0.40) | LMNAKDM4ENPC1ALDH1A1TP53 | |
| SCHEMBL17427482 | 0.66 | TYRO3 (0.38) | METPKMTYRO3NPC1ALDH1A1 | |
| SCHEMBL17409840 | 0.64 | KMT2A (0.48) | KDM4ENPC1ALDH1A1GLARAB9A | |
| SCHEMBL16022024 | 0.64 | SMN1; SMN2 (0.40) | LMNAKDM4ENPC1ALDH1A1RAB9A | |
| SCHEMBL17427481 | 0.64 | HPGD (0.53) | AXLMETMERTKLMNAKDM4E | |
| SCHEMBL17427477 | 0.63 | MET (0.38) | AXLMETLMNATYRO3KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160009693-A1 | HERBICIDAL COMPOUNDS | SYNGENTA LIMITED (GB) | 2016-01-14 | — | — | US | disclosed |
| US-20160009693-A1 | HERBICIDAL COMPOUNDS | SYNGENTA LIMITED (GB) | 2016-01-14 | — | — | US | disclosed |
| WO-2014135654-A1 | HERBICIDAL COMPOUNDS | SYNGENTA LIMITED (GB) | 2014-09-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160009693-A1 | HERBICIDAL COMPOUNDS | DDT, HAX1, CYP4X1 | AXL 3850/4885MET 3504/4885MERTK 4541/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.