Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LGALS8 | O00214 | 4/20 | 0.44 |
| ▸ | LGALS3 | P17931 | 3/20 | 0.43 |
| ▸ | LGALS4 | P56470 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | LGALS9 | O00182 | 1/20 | 0.41 |
| ▸ | LGALS1 | P09382 | 1/20 | 0.41 |
| ▸ | LGALS7; LGALS7B | P47929 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | SLC28A3 | Q9HAS3 | 2/20 | 0.40 |
| ▸ | SELE | P16581 | 1/20 | 0.40 |
| ▸ | IGF2R | P11717 | 1/20 | 0.40 |
| ▸ | SYNJ2 | O15056 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16351477 | 0.91 | IGF2R (0.43) | LGALS8LGALS3LGALS4L3MBTL1MEN1 | |
| SCHEMBL2492336 | 0.87 | LGALS3 (0.43) | LGALS8LGALS3LGALS4L3MBTL1MEN1 | |
| SCHEMBL2489957 | 0.87 | LGALS3 (0.48) | LGALS8LGALS3LGALS4L3MBTL1MEN1 | |
| SCHEMBL28341510 | 0.84 | L3MBTL1 (0.49) | LGALS8L3MBTL1MAPTSLC28A3 | |
| SCHEMBL15128960 | 0.84 | L3MBTL1 (0.49) | LGALS8L3MBTL1MAPTSLC28A3 | |
| SCHEMBL10865539 | 0.82 | LGALS8 (0.48) | LGALS8LGALS3LGALS4 | |
| SCHEMBL22452303 | 0.81 | TLR4 (0.45) | L3MBTL1MEN1KMT2AMAPTPTPN1 | |
| SCHEMBL7702025 | 0.81 | LGALS8 (0.52) | LGALS8LGALS3LGALS4MEN1KMT2A | |
| SCHEMBL2486794 | 0.81 | LGALS8 (0.43) | LGALS8LGALS3LGALS4LGALS9LGALS1 | |
| SCHEMBL21924090 | 0.81 | LGALS8 (0.40) | LGALS8LGALS3LGALS4LGALS9LGALS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180015167-A1 | CROSSLINKABLE TREHALOSE FOR THE COVALENT INCORPORATION IN HYDROGELS AND METHODS OF USE | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 2018-01-18 | — | — | US | disclosed |
| WO-2014160377-A1 | CROSSLINKABLE TREHALOSE FOR THE COVALENT INCORPORATION IN HYDROGELS AND METHODS OF USE | INVIVO THERAPEUTICS CORPORATION (US) | 2014-10-02 | — | — | WO | disclosed |
| US-20140271601-A1 | CROSSLINKABLE TREHALOSE FOR THE COVALENT INCORPORATION IN HYDROGELS AND METHODS OF USE | INVIVO THERAPEUTICS CORPORATION (US) | 2014-09-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180015167-A1 | CROSSLINKABLE TREHALOSE FOR THE COVALENT INCORPORATION IN HYDROGELS AND METHODS OF USE | TREH, TBCA, BMP2 | LGALS8 639/4885LGALS3 621/4885LGALS4 640/4885 |
| US-20140271601-A1 | CROSSLINKABLE TREHALOSE FOR THE COVALENT INCORPORATION IN HYDROGELS AND METHODS OF USE | TREH, TBCA, BMP2 | LGALS8 639/4885LGALS3 621/4885LGALS4 640/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.