Benzoic Acid

Benzoic Acid

SCHEMBL16046263

CCCC(O)C(C)C(O)CC.O=C(O)c1ccccc1.O=S(=O)(O)c1ccccc1

nearest known ligand 0.41

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Known targets — ChEMBL curated mechanism

BTKCACNA1CCACNA1DCACNA1FCACNA1SCACNA2D1CACNA2D2DRD2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQHRH1HTR2AP2RY12

The experimentally established mechanism targets of Benzoic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 3/20 0.41
TSHR P16473 3/20 0.41
MCL1 Q07820 1/20 0.37
RAB9A P51151 3/20 0.36
SLC6A2 P23975 1/20 0.36
SLC6A3 Q01959 1/20 0.36
NPC1 O15118 1/20 0.36
ALOX5 P09917 3/20 0.36
CA12 O43570 2/20 0.36
CA2 P00918 2/20 0.36
CA9 Q16790 2/20 0.36
SLC22A6 Q4U2R8 1/20 0.36
SLC22A8 Q8TCC7 1/20 0.36
ABCC2 Q92887 1/20 0.36
SLC22A12 Q96S37 1/20 0.36
UGT1A7 Q9HAW7 1/20 0.36
SLC22A11 Q9NSA0 1/20 0.36
DAO P14920 1/20 0.36
NAPRT Q6XQN6 1/20 0.36
ALDH1A1 P00352 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzoic Acid SCHEMBL16046814 0.96 SMN1; SMN2 (0.44) SMN1; SMN2TSHRMCL1RAB9ASLC6A2
Benzoic Acid SCHEMBL16047778 0.93 TSHR (0.47) SMN1; SMN2TSHRMCL1RAB9ACA12
SCHEMBL16046060 0.92 TSHR (0.48) SMN1; SMN2TSHRRAB9ANPC1ALDH1A1
Benzoic Acid SCHEMBL1783063 0.89 DAO (0.45) SMN1; SMN2TSHRRAB9ASLC6A2SLC6A3
Benzoic Acid SCHEMBL30602841 0.89 DAO (0.45) SMN1; SMN2TSHRRAB9ASLC6A2SLC6A3
SCHEMBL16048828 0.88 TSHR (0.53) SMN1; SMN2TSHRRAB9ANPC1ALDH1A1
SCHEMBL16045650 0.85 TSHR (0.57) SMN1; SMN2TSHRALDH1A1HSD17B10TRPA1
Benzoic Acid SCHEMBL1786405 0.85 DAO (0.50) SMN1; SMN2TSHRRAB9ASLC6A2SLC6A3
Ethohexadiol SCHEMBL16044663 0.84 LMNA (0.47) SMN1; SMN2TSHRRAB9ASLC6A2SLC6A3
Benzoyl Formic Acid SCHEMBL16044971 0.83 CES2 (0.42) SMN1; SMN2TSHRRAB9ASLC6A2SLC6A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109180843-B Non-phthalate compounds as electron donors for polyolefin catalysts 美国台塑公司 2022-03-01 CN claimed
EP-2969201-B1 NON-PHTHALATE COMPOUNDS AS ELECTRON DONORS FOR POLYOLEFIN CATALYSTS FORMOSA PLASTICS CORP USA (US) 2022-05-04 EP disclosed
CN-109180843-B Non-phthalate compounds as electron donors for polyolefin catalysts 美国台塑公司 2022-03-01 CN disclosed
US-9790291-B2 Non-phthalate compounds as electron donors for polyolefin catalysts FORMOSA PLASTICS CORPORATION, USA (US) 2017-10-17 US disclosed
US-20140275456-A1 NON-PHTHALATE COMPOUNDS AS ELECTRON DONORS FOR POLYOLEFIN CATALYSTS FORMOSA PLASTICS CORPORATION, USA (US) 2014-09-18 US disclosed