SCHEMBL160814

SCHEMBL160814

O=C(OO)c1ccc(Cl)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES2 O00748 3/20 0.56
CES1 P23141 3/20 0.56
ALOX15 P16050 2/20 0.54
TSHR P16473 1/20 0.54
NPC1 O15118 2/20 0.53
RAB9A P51151 2/20 0.53
L3MBTL1 Q9Y468 2/20 0.53
SMN1; SMN2 Q16637 2/20 0.53
CA1 P00915 2/20 0.52
CA2 P00918 2/20 0.52
ALDH1A1 P00352 2/20 0.52
GSK3B P49841 2/20 0.48
SRD5A2 P31213 1/20 0.48
MAPK1 P28482 1/20 0.48
KMT2A Q03164 3/20 0.47
LMNA P02545 2/20 0.47
NR1I2 O75469 1/20 0.47
TP53 P04637 1/20 0.47
AHR P35869 1/20 0.47
TAAR1 Q96RJ0 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
1,4-Dichlorobenzene SCHEMBL27464901 0.89 CES2 (0.59) CES2CES1ALOX15TSHRNPC1
SCHEMBL10591190 0.88 ALDH1A1 (0.47) CES2CES1ALOX15TSHRNPC1
SCHEMBL1286650 0.87 CES2 (0.48) CES2CES1TSHRNPC1RAB9A
Benzoyl Peroxide SCHEMBL10457039 0.86 LMNA (0.63) CES2CES1ALOX15TSHRNPC1
Chlorobenzene SCHEMBL1781430 0.84 LMNA (0.54) CES2CES1ALOX15TSHRNPC1
SCHEMBL28597958 0.84 CES2 (0.46) CES2CES1TSHRNPC1RAB9A
SCHEMBL29112554 0.84 CES2 (0.46) CES2CES1TSHRNPC1RAB9A
SCHEMBL11880655 0.84 CES2 (0.46) CES2CES1TSHRNPC1RAB9A
SCHEMBL18351660 0.83 RAB9A (0.41) CES2CES1ALOX15TSHRNPC1
SCHEMBL28775846 0.82 CES2 (0.59) CES2CES1ALOX15TSHRNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 801 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120136745-A Compound with neuroprotective activity, preparation method and application 中山大学 2025-06-13 CN claimed
CN-114195640-B Synthesis process of hydroxytyrosol and intermediate thereof 攀枝花学院 2024-03-12 CN claimed
CN-116925141-A Synthesis and research of novel organophosphorus flame retardant 深圳有为技术控股集团有限公司 2023-10-24 CN claimed
EP-3935109-B1 ONE-PART ANAEROBICALLY CURABLE COMPOSITIONS HENKEL AG & CO KGAA (DE) 2023-08-09 EP claimed
WO-2023088864-A1 METHOD FOR PREPARING POLYMERS LANXESS DEUTSCHLAND GMBH (DE) 2023-05-25 WO claimed
CN-114195640-A Synthetic process of hydroxytyrosol and intermediate thereof 攀枝花学院 2022-03-18 CN claimed
EP-3174932-B1 CURE ACCELERATORS FOR ANAEROBIC CURABLE COMPOSITIONS Henkel IP & Holding GmbH (DE) 2021-06-09 EP claimed
CN-107365422-B Hydrophilic modification method of polyglycidyl methacrylate or copolymer thereof and modified material 中国科学院过程工程研究所 2020-12-01 CN claimed
EP-3194393-B1 1,3,4-THIADIAZOLES HAVING A HERBICIDAL ACTIVITY, THEIR AGRONOMICAL COMPOSITIONS AND RELATIVE USE ISAGRO SPA (IT) 2020-03-11 EP claimed
EP-3253561-B1 PROCESS FOR PRODUCING MODIFIED OLEFIN POLYMER IN AN EXTRUDER BOREALIS AG (AT) 2019-05-08 EP claimed
EP-0109532-B2 PROCESS FOR MANUFACTURING MOFIFIED OLEFINIC POLYMERS Montedison S.p.A. (IT) 1992-01-29 EP claimed
US-5055582-A Process for preparing thromboxane A2 antagonists NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) 1991-10-08 US claimed
EP-0204531-B1 PRODUCTION OF MOLDED VULCANISED RUBBER ARTICLES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1990-09-12 EP claimed
EP-0109532-B1 PROCESS FOR MANUFACTURING MOFIFIED OLEFINIC POLYMERS Montedison S.p.A. (IT) 1989-01-04 EP claimed
EP-0096500-B1 TWO-PART SELF-INDICATING ADHESIVE COMPOSITION LOCTITE (IRELAND) Ltd. (IE) 1988-01-07 EP claimed
EP-0072299-B1 4-METHYL-6-PHENYL-PYRIDAZINE DERIVATIVES ACTIVE ON THE CENTRAL NERVOUS SYSTEM SANOFI S.A. (FR) 1986-12-17 EP claimed
EP-0080338-B1 POLYMERIZATION OF POLYOL (ALLYL CARBONATE) USING POLYMERIZATION INITIATORS OF SHORT AND LONG HALF LIVES PPG INDUSTRIES, INC. (US) 1986-05-07 EP claimed
EP-0001954-B1 PROCESS FOR THE MANUFACTURE OF SAFETY GLASS AND PRODUCT OBTAINED ACCORDING TO THIS PROCESS COMMISSARIAT A L'ENERGIE ATOMIQUE Etablissement de Caractère Scientifique Technique et Industriel (FR) 1981-08-26 EP claimed
US-4221660-A AROMATIC PERCARBOXYLIC ACID, FOR WATER SYSTEMS STERLING DRUG INC. (US) 1980-09-09 US claimed
US-4163743-A Beta-lactams, their production from azetidine carboxylic acids, intermediates thereto and derivatives thereof RESEARCH CORPORATION (US) 1979-08-07 US claimed