Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.89 |
| ▸ | RAB9A | P51151 | 3/20 | 0.89 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.89 |
| ▸ | NPC1 | O15118 | 2/20 | 0.89 |
| ▸ | JUN | P05412 | 2/20 | 0.89 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.89 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.89 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.89 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.69 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.69 |
| ▸ | CYP1A2 | P05177 | 8/20 | 0.68 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.68 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.68 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.68 |
| ▸ | LMNA | P02545 | 1/20 | 0.68 |
| ▸ | F3 | P13726 | 1/20 | 0.68 |
| ▸ | RECQL | P46063 | 1/20 | 0.68 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5598852 | 0.94 | MAPT (1.00) | MAPTRAB9AKDM4ENPC1JUN | |
| SCHEMBL5598850 | 0.94 | MAPT (1.00) | MAPTRAB9AKDM4ENPC1JUN | |
| Hydrochloric Acid SCHEMBL11971085 | 0.93 | MAPT (0.96) | MAPTRAB9AKDM4ENPC1JUN | |
| Hydrochloric Acid SCHEMBL11971079 | 0.93 | MAPT (0.96) | MAPTRAB9AKDM4ENPC1JUN | |
| SCHEMBL28356916 | 0.88 | MAPT (0.81) | MAPTRAB9AKDM4ENPC1JUN | |
| SCHEMBL334615 | 0.85 | RAB9A (0.76) | MAPTRAB9AKDM4ENPC1JUN | |
| SCHEMBL755249 | 0.85 | RAB9A (0.76) | MAPTRAB9AKDM4ENPC1JUN | |
| SCHEMBL334614 | 0.85 | RAB9A (0.76) | MAPTRAB9AKDM4ENPC1JUN | |
| SCHEMBL29416684 | 0.85 | RAB9A (0.76) | MAPTRAB9AKDM4ENPC1JUN | |
| SCHEMBL28431765 | 0.85 | ALDH1A1 (0.76) | MAPTRAB9AKDM4ENPC1JUN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9925153-B2 | Therapeutic agents for skin diseases and conditions | STC.UNM (US) | 2018-03-27 | — | — | US | disclosed |
| US-20160287531-A1 | THERAPEUTIC AGENTS FOR SKIN DISEASES AND CONDITIONS | STC.UNM | 2016-10-06 | — | — | US | disclosed |
| US-9187397-B2 | Therapeutic curcumin derivatives | STC.UNM (US) | 2015-11-17 | — | — | US | disclosed |
| US-8841326-B2 | Therapeutic curcumin derivatives | STC.UNM (US) | 2014-09-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160287531-A1 | THERAPEUTIC AGENTS FOR SKIN DISEASES AND CONDITIONS | CUTA, TSLP, ELANE | MAPT 790/4885RAB9A 3557/4885KDM4E 3199/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.