Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1611568 | 0.90 | KDM1A (0.34) | — | |
| SCHEMBL1611558 | 0.87 | PDE3B (0.32) | PDE3BPDE3A | |
| SCHEMBL1611478 | 0.87 | CA1 (0.32) | — | |
| SCHEMBL1612165 | 0.86 | GABRP (0.35) | PDE3BPDE3A | |
| SCHEMBL112624 | 0.85 | PDE3B (0.34) | PDE3BPDE3A | |
| SCHEMBL1610695 | 0.84 | HTT (0.39) | PDE3BPDE3A | |
| SCHEMBL1610360 | 0.83 | CYP11B1 (0.36) | — | |
| SCHEMBL16681049 | 0.81 | PDE3B (0.41) | PDE3BPDE3A | |
| SCHEMBL1609897 | 0.81 | MAPT (0.41) | — | |
| SCHEMBL1609844 | 0.81 | KIF11 (0.38) | PDE3BPDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2069338-B1 | INSECTICIDAL ISOXAZOLINES | BAYER CROPSCIENCE AG (DE) | 2012-11-28 | — | — | EP | disclosed |
| EP-2332937-A1 | Insecticidal isoxazolines | Bayer CropScience AG (DE) | 2011-06-15 | — | — | EP | disclosed |
| EP-2330106-A1 | Insecticidal isoxazolines | Bayer CropScience AG (DE) | 2011-06-08 | — | — | EP | disclosed |
| US-20110086886-A2 | INSECTICIDAL ISOXAZOLINES | BAYER CROPSCIENCE AG (DE) | 2011-04-14 | — | — | US | disclosed |
| US-20100249191-A1 | N-Methyl benzamide derivatives | BAYER CROPSCIENCE SA (FR) | 2010-09-30 | — | — | US | disclosed |
| EP-2069338-A1 | INSECTICIDAL ISOXAZOLINES | Bayer CropScience AG (DE) | 2009-06-17 | — | — | EP | disclosed |
| WO-2008019760-A1 | INSECTICIDAL ISOXAZOLINES | BAYER CROPSCIENCE AG (DE) | 2008-02-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110086886-A2 | INSECTICIDAL ISOXAZOLINES | HAX1, INA, CYCS | PDE3B 1230/4885PDE3A 1339/4885 |
| US-20100249191-A1 | N-Methyl benzamide derivatives | GNMT, SCN1A, INA | PDE3B 1252/4885PDE3A 1173/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.