Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 2/20 | 0.41 |
| ▸ | RORA | P35398 | 1/20 | 0.41 |
| ▸ | RORC | P51449 | 1/20 | 0.41 |
| ▸ | RORB | Q92753 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CCR2 | P41597 | 1/20 | 0.39 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.39 |
| ▸ | TSPO | P30536 | 2/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.36 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16099114 | 0.83 | ALDH1A1 (0.42) | PGRRORARORCRORBALDH1A1 | |
| SCHEMBL16104960 | 0.83 | PTGER4 (0.57) | PGRRORARORCRORBALDH1A1 | |
| SCHEMBL16093698 | 0.79 | ALDH1A1 (0.58) | PGRRORARORCRORBALDH1A1 | |
| SCHEMBL16093794 | 0.79 | CNR2 (0.48) | PGRALDH1A1HPGDNPSR1MAPT | |
| SCHEMBL16099757 | 0.79 | PTGER4 (0.54) | PGRRORARORCRORBALDH1A1 | |
| SCHEMBL16093823 | 0.79 | HPGD (0.52) | PGRRORARORCRORBALDH1A1 | |
| SCHEMBL30213423 | 0.75 | KCNA3 (0.49) | PGRRORARORCRORBALDH1A1 | |
| SCHEMBL16097572 | 0.73 | ALDH1A1 (0.44) | PGRRORARORCRORBALDH1A1 | |
| SCHEMBL16093752 | 0.73 | HPGD (0.44) | PGRRORARORCRORBALDH1A1 | |
| SCHEMBL16099561 | 0.73 | KDM4E (0.47) | PGRRORARORCRORBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014153043-A1 | COMPOUNDS AND METHODS FOR TREATING CANCERS | HEALTH RESEARCH, INC. (US) | 2014-09-25 | — | — | WO | disclosed |