Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 2/20 | 0.57 |
| ▸ | CRY1 | Q16526 | 4/20 | 0.40 |
| ▸ | CRY2 | Q49AN0 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 6/20 | 0.36 |
| ▸ | PER2 | O15055 | 2/20 | 0.36 |
| ▸ | RORC | P51449 | 2/20 | 0.36 |
| ▸ | PGR | P06401 | 2/20 | 0.36 |
| ▸ | RORA | P35398 | 1/20 | 0.36 |
| ▸ | RORB | Q92753 | 1/20 | 0.36 |
| ▸ | ICMT | O60725 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16099114 | 0.85 | ALDH1A1 (0.42) | PTGER4ALDH1A1HPGDMAPTCNR2 | |
| SCHEMBL16093825 | 0.83 | PGR (0.41) | PTGER4ALDH1A1HPGDTP53MAPT | |
| SCHEMBL16093698 | 0.81 | ALDH1A1 (0.58) | PTGER4ALDH1A1HPGDTP53MAPT | |
| SCHEMBL16104959 | 0.78 | HPGD (0.54) | PTGER4CRY1CRY2ALDH1A1HPGD | |
| SCHEMBL16099561 | 0.75 | KDM4E (0.47) | ALDH1A1HPGDMAPTCNR2RORC | |
| SCHEMBL16093752 | 0.75 | HPGD (0.44) | ALDH1A1HPGDMAPTSMN1; SMN2CNR2 | |
| SCHEMBL16097572 | 0.75 | ALDH1A1 (0.44) | ALDH1A1HPGDTP53MAPTSMN1; SMN2 | |
| SCHEMBL15774378 | 0.73 | PTGER4 (1.00) | PTGER4CRY1CRY2ALDH1A1HPGD | |
| SCHEMBL16099757 | 0.73 | PTGER4 (0.54) | PTGER4ALDH1A1HPGDMAPTCNR2 | |
| SCHEMBL16093634 | 0.71 | MAPT (0.53) | MAPTCNR2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014153043-A1 | COMPOUNDS AND METHODS FOR TREATING CANCERS | HEALTH RESEARCH, INC. (US) | 2014-09-25 | — | — | WO | disclosed |