Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1611160 | 0.98 | HTT (0.44) | CYP2A6HTTRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL1610892 | 0.98 | HTT (0.44) | CYP2A6HTTRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL1612718 | 0.93 | CYP2A6 (0.46) | CYP2A6HTTRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL1611178 | 0.84 | CYP2A6 (0.50) | CYP2A6RAB9ANPC1SMN1; SMN2L3MBTL1 | |
| SCHEMBL6320373 | 0.84 | ALDH1A1 (0.39) | RAB9ANPC1SMN1; SMN2TSHRKCNH2 | |
| SCHEMBL1609682 | 0.81 | ALDH1A1 (0.44) | CYP2A6SMN1; SMN2ACHEHPGDKDM4E | |
| SCHEMBL5878874 | 0.81 | TRPA1 (0.42) | L3MBTL1NFE2L2HPGDMAPTNPSR1 | |
| SCHEMBL38728 | 0.80 | LMNA (0.46) | CYP2A6SMN1; SMN2TDP1MAPT | |
| SCHEMBL2323474 | 0.79 | ALDH1A1 (0.52) | ACHEKDM4EMAPT | |
| SCHEMBL1610146 | 0.79 | TNNC1 (0.43) | ACHEKDM4ETNNC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9074266-B2 | 2,9-dipyridyl-1,10-phenanthroline derivatives useful as actinide ligands, method for synthesizing same, and uses thereof | Commissariat à l'énergie atomique et aux énergies alternatives (FR) | 2015-07-07 | — | — | US | disclosed |
| US-20140030172-A1 | 2,9-DIPYRIDYL-1,10-PHENANTHROLINE DERIVATIVES USEFUL AS ACTINIDE LIGANDS, METHOD FOR SYNTHESIZING SAME, AND USES THEREOF | UNIVERSITE DE NANTES (FR) | 2014-01-30 | — | — | US | disclosed |
| US-20110087034-A1 | Organic Semiconductor Material | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 2011-04-14 | — | — | US | disclosed |
| EP-2248818-A1 | ORGANIC SEMICONDUCTOR MATERIAL | Sumitomo Chemical Company, Limited (JP) | 2010-11-10 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140030172-A1 | 2,9-DIPYRIDYL-1,10-PHENANTHROLINE DERIVATIVES USEFUL AS ACTINIDE LIGANDS, METHOD FOR SYNTHESIZING SAME, AND USES THEREOF | NRP1, AHR, NR0B1 | CYP2A6 1140/4885HTT 2749/4885RAB9A 477/4885 |
| US-20110087034-A1 | Organic Semiconductor Material | OR10J3, TST, OR51E2 | CYP2A6 1465/4885HTT 774/4885RAB9A 3050/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.