Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 2/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 5/20 | 0.33 |
| ▸ | CTSC | P53634 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.32 |
| ▸ | CCR2 | P41597 | 2/20 | 0.32 |
| ▸ | F2 | P00734 | 1/20 | 0.32 |
| ▸ | F10 | P00742 | 1/20 | 0.32 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1609805 | 0.90 | ALDH1A1 (0.35) | TSHRMAPK1ALDH1A1CYP3A4F10 | |
| SCHEMBL1610992 | 0.88 | KDM1A (0.34) | KDM1ASLC6A4BACE1CA1CA2 | |
| SCHEMBL1610621 | 0.87 | KDM1A (0.36) | KDM1ASLC6A4BACE1TSHRMAPK1 | |
| SCHEMBL1611211 | 0.85 | KDM1A (0.40) | KDM1ASLC6A4BACE1CTSCTSHR | |
| SCHEMBL1609340 | 0.83 | CYP3A4 (0.36) | TSHRMAPK1ALDH1A1CYP3A4F10 | |
| SCHEMBL1609341 | 0.82 | NPY5R (0.40) | KDM1ASLC6A4BACE1TSHRMAPK1 | |
| SCHEMBL27791817 | 0.81 | SLC6A4 (0.41) | KDM1ASLC6A4BACE1F2F10 | |
| SCHEMBL3110578 | 0.81 | NLRP3 (0.39) | KDM1ASLC6A4CYP3A4CCR2NPC1 | |
| SCHEMBL1611568 | 0.80 | KDM1A (0.34) | KDM1ASLC6A4BACE1F2F10 | |
| SCHEMBL20508225 | 0.79 | GPR52 (0.40) | KDM1ACTSCCCR2F2F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2069338-B1 | INSECTICIDAL ISOXAZOLINES | BAYER CROPSCIENCE AG (DE) | 2012-11-28 | — | — | EP | disclosed |
| CN-102731403-A | Insecticidal isoxazolines | BAYER CROPSCIENCE AG | 2012-10-17 | — | — | CN | disclosed |
| CN-101522672-B | Insecticidal isoxazolines | BAYER CROPSCIENCE AG | 2012-07-18 | — | — | CN | disclosed |
| US-20110086886-A2 | INSECTICIDAL ISOXAZOLINES | BAYER CROPSCIENCE AG (DE) | 2011-04-14 | — | — | US | disclosed |
| US-20100249191-A1 | N-Methyl benzamide derivatives | BAYER CROPSCIENCE SA (FR) | 2010-09-30 | — | — | US | disclosed |
| CN-101522672-A | Insecticidal isoxazolines | BAYER CROPSCIENCE AG (DE) | 2009-09-02 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110086886-A2 | INSECTICIDAL ISOXAZOLINES | HAX1, INA, CYCS | KDM1A 699/4885SLC6A4 3113/4885BACE1 2820/4885 |
| US-20100249191-A1 | N-Methyl benzamide derivatives | GNMT, SCN1A, INA | KDM1A 133/4885SLC6A4 2842/4885BACE1 4066/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.