Sugi Predict

Sugi Predict / Compounds / SCHEMBL1611698

SCHEMBL1611698

SCHEMBL1611698

[C]#Cc1ccc(C(C)(C)C)cc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KIF11 P52732 2/20 0.54
▸ TSHR P16473 1/20 0.50
▸ LMNA P02545 1/20 0.48
▸ TYR P14679 1/20 0.48
▸ RARB P10826 2/20 0.47
▸ RARG P13631 1/20 0.47
▸ ALDH1A1 P00352 4/20 0.39
▸ HPGD P15428 2/20 0.38
▸ NPC1 O15118 1/20 0.38
▸ MAPT P10636 1/20 0.38
▸ MAPK1 P28482 1/20 0.38
▸ RAB9A P51151 1/20 0.38
▸ HDAC1 Q13547 1/20 0.38
▸ SLC22A2 O15244 1/20 0.38
▸ SLC22A1 O15245 1/20 0.38
▸ SLC22A3 O75751 1/20 0.38
▸ SMN1; SMN2 Q16637 1/20 0.38
▸ BCHE P06276 3/20 0.37
▸ ACHE P22303 3/20 0.37
▸ ALOX15 P16050 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19875742 0.80 KIF11 (0.56) KIF11TSHRLMNATYRRARB
SCHEMBL25413986 0.80 RARB (0.65) KIF11TSHRLMNATYRRARB
SCHEMBL2868881 0.80 KIF11 (0.56) KIF11TSHRLMNATYRRARB
SCHEMBL424728 0.78 TSHR (0.73) KIF11TSHRLMNATYRALDH1A1
SCHEMBL69655 0.76 KIF11 (0.86) KIF11TSHRLMNATYRRARB
SCHEMBL1611163 0.76 KIF11 (0.52) KIF11TSHRLMNATYRRARB
SCHEMBL165547 0.76 KIF11 (0.52) KIF11TSHRLMNATYRRARB
SCHEMBL1041507 0.76 KIF11 (0.52) KIF11TSHRALDH1A1EPHX2
SCHEMBL10011603 0.76 KIF11 (0.52) KIF11TSHRLMNATYRRARB
SCHEMBL9506892 0.76 TSHR (0.48) KIF11TSHRLMNATYRRARB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230413661-A1 LUMINESCENT GOLD(III) COMPOUNDS WITH THERMALLY STIMULATED DELAYED PHOSPHORESCENCE (TSDP) PROPERTY FOR ORGANIC LIGHT-EMITTING DEVICES AND THEIR PREPARATION THE UNIVERSITY OF HONG KONG (CN) 2023-12-21 — — US claimed
CN-111269711-A Transition metal luminescent complexes and methods of use 香港大学 2020-06-12 — — CN claimed
CN-101248056-A Non-steroidal progesterone receptor modulators BAYER SCHERING PHARMA AG (DE) 2008-08-20 — — CN claimed
CN-101248066-A Non-steroidal progesterone receptor modulators BAYER SCHERING PHARMA AG (DE) 2008-08-20 — — CN claimed
EP-1902049-A2 NON-STEROIDAL PROGESTERONE RECEPTOR MODULATORS Bayer Schering Pharma Aktiengesellschaft (DE) 2008-03-26 — — EP claimed
US-20070010514-A1 Non-steroidal progesterone receptor modulators BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) 2007-01-11 — — US claimed
WO-2006136461-A2 NON-STEROIDAL PROGESTERONE RECEPTOR MODULATORS BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) 2006-12-28 — — WO claimed
CN-111269711-A Transition metal luminescent complexes and methods of use 香港大学 2020-06-12 — — CN disclosed
US-20200031778-A1 NOVEL 5-SUBSTITUTED IMIDAZOLYLMETHYL DERIVATIVES BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2020-01-30 — — US disclosed
US-8466176-B2 Fungicide hydroximoyl-tetrazole derivatives BAYER CROPSCIENCE AG (DE) 2013-06-18 — — US disclosed
US-20110105566-A1 FUNGICIDE HYDROXIMOYL-TETRAZOLE DERIVATIVES BAYER INTELLECTUAL PROPERTY GMBH (DE) 2011-05-05 — — US disclosed
US-20110087034-A1 Organic Semiconductor Material SUMITOMO CHEMICAL COMPANY LIMITED (JP) 2011-04-14 — — US disclosed
EP-2248818-A1 ORGANIC SEMICONDUCTOR MATERIAL Sumitomo Chemical Company, Limited (JP) 2010-11-10 — — EP disclosed
US-5414007-A Skin disorders ALLERGAN, INC. (US) 1995-05-09 — — US disclosed
US-5264456-A Skin disorders, anticarcinogenic agents, antiarthritic agents, immunology or wound healing agents ALLERGAN, INC. (US) 1993-11-23 — — US disclosed
EP-0318860-B1 SUBSTITUTED ALKYLAMINE DERIVATIVES BANYU PHARMACEUTICAL CO., LTD. (JP) 1993-06-16 — — EP disclosed
US-5175185-A Antiacne agents ALLERGAN, INC. (US) 1992-12-29 — — US disclosed
EP-0436398-A1 Acetylenes disubstituted with a heteroaromatic group and a substituted phenyl group having retinoid like activity ALLERGAN, INC. (US) 1991-07-10 — — EP disclosed
US-5013744-A Skin disorders ALLERGAN, INC. (US) 1991-05-07 — — US disclosed
EP-0318860-A2 Substituted alkylamine derivatives BANYU PHARMACEUTICAL CO., LTD. (JP) 1989-06-07 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230413661-A1 LUMINESCENT GOLD(III) COMPOUNDS WITH THERMALLY STIMULATED DELAYED PHOSPHORESCENCE (TSDP) PROPERTY FOR ORGANIC LIGHT-EMITTING DEVICES AND THEIR PREPARATION OCIAD1, OCIAD2, OSGEP KIF11 3117/4885TSHR 443/4885LMNA 4637/4885
US-20110105566-A1 FUNGICIDE HYDROXIMOYL-TETRAZOLE DERIVATIVES HAAO, CYP51A1, HPD KIF11 2467/4885TSHR 2765/4885LMNA 3100/4885
US-20200031778-A1 NOVEL 5-SUBSTITUTED IMIDAZOLYLMETHYL DERIVATIVES IPMK, PIP5K1B, PIP5K1C KIF11 4268/4885TSHR 3409/4885LMNA 3691/4885
US-20070010514-A1 Non-steroidal progesterone receptor modulators PGR, PGRMC1, CYP19A1 KIF11 3275/4885TSHR 123/4885LMNA 1568/4885
US-20110087034-A1 Organic Semiconductor Material OR10J3, TST, OR51E2 KIF11 3208/4885TSHR 2994/4885LMNA 4544/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.