Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.40 |
| ▸ | CES1 | P23141 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 4/20 | 0.37 |
| ▸ | CA2 | P00918 | 4/20 | 0.37 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.35 |
| ▸ | ORAI2 | Q96SN7 | 1/20 | 0.35 |
| ▸ | ORAI3 | Q9BRQ5 | 1/20 | 0.35 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.35 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.34 |
| ▸ | BAD | Q92934 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | MMP1 | P03956 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
| ▸ | MMP8 | P22894 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4614322 | 0.97 | CES2 (0.42) | CES2CES1CA1CA2ORAI1 | |
| Ammonia Solution, Strong SCHEMBL4615643 | 0.95 | CES2 (0.40) | CES2CES1CA1CA2ORAI1 | |
| SCHEMBL11323370 | 0.95 | CES2 (0.40) | CES2CES1CA1CA2ORAI1 | |
| SCHEMBL3162019 | 0.87 | HSD11B1 (0.48) | PTGS1HSD11B1 | |
| SCHEMBL11859127 | 0.86 | CA1 (0.33) | CA1CA2 | |
| SCHEMBL9153089 | 0.83 | CA1 (0.36) | CA1CA2ALDH1A1 | |
| SCHEMBL5354761 | 0.78 | NR4A2 (0.58) | CA1CA2CA7CA9MMP1 | |
| SCHEMBL8334157 | 0.78 | MAPK14 (0.53) | PTGS1 | |
| SCHEMBL4070877 | 0.77 | PGR (0.42) | CA2BCL2L1BADPTGS1ALDH1A1 | |
| SCHEMBL10606718 | 0.75 | ESR1 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 206 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120136752-A | Alkenyl substituted tellurium organic compound, preparation method and application thereof in resisting plant pathogenic bacteria | 贵州大学 | 2025-06-13 | — | — | CN | claimed |
| CN-118834161-A | Preparation method of 3-sulfonyl-5-acetyl-1, 4 dihydropyridine compound | 西北工业大学 | 2024-10-25 | — | — | CN | claimed |
| CN-117926289-A | Method for electrochemically synthesizing N-sulfoamidine derivatives under mild condition | 湘潭大学 | 2024-04-26 | — | — | CN | claimed |
| CN-114230496-B | Aromatic sulfinic acid compound and preparation method thereof | 达高工业技术研究院(广州)有限公司 | 2023-07-14 | — | — | CN | claimed |
| CN-109796380-A | 2-allyl-3-sulfonyl-3-butenoate compound and preparation method thereof | 南京工业大学 | 2019-05-24 | — | — | CN | claimed |
| US-9650330-B2 | Process for the synthesis of aryl sulfones | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2017-05-16 | — | — | US | claimed |
| US-20160304447-A1 | A PROCESS FOR THE SYNTHESIS OF ARYL SULFONES | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2016-10-20 | — | — | US | claimed |
| WO-2015087352-A1 | A PROCESS FOR THE SYNTHESIS OF ARYL SULFONES | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2015-06-18 | — | — | WO | claimed |
| EP-1506170-B1 | METHOD FOR PRODUCING BICALUTAMIDE | HELM AG (DE) | 2008-02-27 | — | — | EP | claimed |
| US-7323584-B2 | Process for preparing N-(4′-cyano-3′-trifluoromethylphenyl)-3-(4″-fluorophenylsulfonyl)-2-hydroxy-2-methylpropionamide | HELM AG (DE) | 2008-01-29 | — | — | US | claimed |
| US-20050033082-A1 | Method for producing bicalutamide | CF PHARMA GYOGYSZERGYARTO KFT. (HU) | 2005-02-10 | — | — | US | claimed |
| EP-0687671-B1 | Method for the preparation of 4-fluorothiophenol | BAYER AG (DE) | 1997-09-10 | — | — | EP | claimed |
| US-5659088-A | Process for the preparation of 4-fluorothiophenol | BAYER AKTIENGESELLSCHAFT (DE) | 1997-08-19 | — | — | US | claimed |
| US-5008369-A | Preparation of polysulfones | EASTMAN KODAK COMPANY (US) | 1991-04-16 | — | — | US | claimed |
| JP-8003130-A | — | — | None | — | — | JP | disclosed |
| US-12336981-B2 | Compounds and compositions for the inhibition of NAMPT | VALO HEALTH, INC. (US) | 2025-06-24 | — | — | US | disclosed |
| CN-116356354-B | Preparation method of 2-aryl-3-sulfonyl substituted tetrahydropyrrole and piperidine compounds | 遵义医科大学 | 2025-06-13 | — | — | CN | disclosed |
| EP-0478874-A2 | Novel 2-substituted alkyl-3-carboxy carbapenems as antibiotics and a method of producing them | AMERICAN CYANAMID COMPANY (US) | 1992-04-08 | — | — | EP | disclosed |
| US-5068232-A | Bactericides | AMERICAN CYANAMID COMPANY (US) | 1991-11-26 | — | — | US | disclosed |
| US-5008369-A | Preparation of polysulfones | EASTMAN KODAK COMPANY (US) | 1991-04-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12336981-B2 | Compounds and compositions for the inhibition of NAMPT | NAMPT, NNMT, NNT | CES2 618/4885CES1 649/4885CA1 3301/4885 |
| US-20160304447-A1 | A PROCESS FOR THE SYNTHESIS OF ARYL SULFONES | ARSA, TPST2, STS | CES2 1421/4885CES1 1735/4885CA1 3612/4885 |
| US-20050033082-A1 | Method for producing bicalutamide | BRDT, NPEPPS, TET3 | CES2 175/4885CES1 1507/4885CA1 359/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.