Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 5/20 | 0.53 |
| ▸ | THRB | P10828 | 3/20 | 0.50 |
| ▸ | THRA | P10827 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | S1PR2 | O95136 | 2/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.42 |
| ▸ | RARB | P10826 | 1/20 | 0.41 |
| ▸ | PLK1 | P53350 | 1/20 | 0.41 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16124573 | 0.91 | THRB (0.53) | SPHK1THRBTHRAALDH1A1NPC1 | |
| SCHEMBL27999257 | 0.87 | THRB (0.54) | SPHK1THRBTHRAALDH1A1HPGD | |
| SCHEMBL16124599 | 0.84 | PPARA (0.48) | SPHK1 | |
| SCHEMBL13417053 | 0.83 | SPHK1 (0.40) | SPHK1THRBTHRAPTGS2 | |
| SCHEMBL16124578 | 0.81 | SPHK1 (0.52) | SPHK1THRBTHRAALDH1A1HPGD | |
| SCHEMBL13396529 | 0.81 | SPHK1 (0.39) | SPHK1PTGS2 | |
| SCHEMBL13416272 | 0.80 | PTGS2 (0.40) | SPHK1THRBNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL17294884 | 0.79 | THRB (0.55) | THRBTHRAALDH1A1HPGDHSD17B10 | |
| SCHEMBL10664870 | 0.78 | THRB (0.62) | THRBTHRAALDH1A1HSD17B10SMN1; SMN2 | |
| SCHEMBL13396540 | 0.78 | HTR2A (0.39) | SPHK1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140288142-A1 | NITRIC OXIDE DONOR COMPOUNDS | NICOX SA (FR) | 2014-09-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140288142-A1 | NITRIC OXIDE DONOR COMPOUNDS | NOS3, NOS2, NOS1 | SPHK1 2029/4885THRB 2051/4885THRA 3693/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.