Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 6/20 | 0.48 |
| ▸ | PPARG | P37231 | 4/20 | 0.48 |
| ▸ | ACHE | P22303 | 3/20 | 0.45 |
| ▸ | SPHK1 | Q9NYA1 | 4/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | PTGIR | P43119 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16124574 | 0.92 | ALOX5 (0.48) | PPARAPPARGACHECYP2D6 | |
| SCHEMBL13416287 | 0.84 | ACHE (0.43) | PPARAPPARGACHECYP2D6 | |
| SCHEMBL16124592 | 0.84 | SPHK1 (0.53) | SPHK1 | |
| SCHEMBL16124582 | 0.83 | PPARA (0.49) | PPARAPPARGACHESPHK1CYP2D6 | |
| SCHEMBL13396518 | 0.83 | ALOX5 (0.41) | PPARAPPARGACHE | |
| SCHEMBL13416274 | 0.81 | ACHE (0.44) | ACHECYP2D6 | |
| SCHEMBL13396481 | 0.80 | ALOX5 (0.42) | ACHE | |
| SCHEMBL28364877 | 0.79 | PPARA (0.56) | PPARAPPARGACHECYP2D6 | |
| SCHEMBL16124597 | 0.79 | ACHE (0.48) | PPARAPPARGACHECYP2D6PTGIR | |
| SCHEMBL1790266 | 0.78 | PPARA (0.57) | PPARAPPARGACHECYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140288142-A1 | NITRIC OXIDE DONOR COMPOUNDS | NICOX SA (FR) | 2014-09-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140288142-A1 | NITRIC OXIDE DONOR COMPOUNDS | NOS3, NOS2, NOS1 | PPARA 2870/4885PPARG 3056/4885ACHE 394/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.