Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.61 |
| ▸ | P2RY10 | O00398 | 4/20 | 0.53 |
| ▸ | GPR174 | Q9BXC1 | 4/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | GMNN | O75496 | 1/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | PRKCA | P17252 | 1/20 | 0.46 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27825794 | 1.00 | LMNA (0.61) | LMNAP2RY10GPR174MAPTMAPK1 | |
| SCHEMBL31207053 | 1.00 | LMNA (0.61) | LMNAP2RY10GPR174MAPTMAPK1 | |
| SCHEMBL27825787 | 1.00 | LMNA (0.61) | LMNAP2RY10GPR174MAPTMAPK1 | |
| SCHEMBL31207140 | 1.00 | LMNA (0.61) | LMNAP2RY10GPR174MAPTMAPK1 | |
| SCHEMBL359909 | 1.00 | LMNA (0.61) | LMNAP2RY10GPR174MAPTMAPK1 | |
| SCHEMBL359908 | 1.00 | LMNA (0.61) | LMNAP2RY10GPR174MAPTMAPK1 | |
| Hydrochloric Acid SCHEMBL27805232 | 0.98 | LMNA (0.59) | LMNAP2RY10GPR174MAPTMAPK1 | |
| SCHEMBL31118982 | 0.98 | LMNA (0.59) | LMNAP2RY10GPR174MAPTMAPK1 | |
| SCHEMBL16124705 | 0.93 | LMNA (0.50) | LMNAP2RY10GPR174MAPTMAPK1 | |
| SCHEMBL2820728 | 0.86 | ALDH1A1 (0.41) | LMNAP2RY10GPR174MAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140288142-A1 | NITRIC OXIDE DONOR COMPOUNDS | NICOX SA (FR) | 2014-09-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140288142-A1 | NITRIC OXIDE DONOR COMPOUNDS | NOS3, NOS2, NOS1 | LMNA 4506/4885P2RY10 13/4885GPR174 1153/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.