Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 1/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.39 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.32 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 3/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.32 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.32 |
| ▸ | CES2 | O00748 | 1/20 | 0.32 |
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15894730 | 0.84 | PTPN1 (0.38) | PTPN1SERPINE1HTTPOLBALDH1A1 | |
| SCHEMBL11920353 | 0.79 | AR (0.41) | LMNAMAPTHTTPOLBKMT2A | |
| SCHEMBL16127934 | 0.78 | SCN1A (0.40) | SMN1; SMN2LMNAPOLBKMT2A | |
| SCHEMBL11920352 | 0.78 | TSHR (0.44) | ALDH1A1 | |
| SCHEMBL19316660 | 0.77 | PTPN1 (0.46) | ADRB2ADRB1ADRB3PTPN1UTS2R | |
| SCHEMBL18269756 | 0.77 | LMNA (0.42) | HPGDSMN1; SMN2DRD3NPC1RAB9A | |
| SCHEMBL22475351 | 0.75 | AR (0.39) | MAPTPOLBALDH1A1KMT2A | |
| SCHEMBL22417596 | 0.74 | TSHR (0.40) | — | |
| SCHEMBL13135914 | 0.74 | ADRB2 (0.62) | ADRB2ADRB1ADRB3HRH3KDM4E | |
| SCHEMBL15894729 | 0.73 | TSHR (0.44) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2976323-B1 | HIGH REFRACTIVE INDEX ADDITION-FRAGMENTATION AGENTS | 3M INNOVATIVE PROPERTIES CO (US) | 2020-07-15 | — | — | EP | disclosed |
| US-20190105237-A1 | HIGH REFRACTIVE INDEX ADDITION-FRAGMENTATION AGENTS | 3M INNOVATIVE PROPERTIES CO (US) | 2019-04-11 | — | — | US | disclosed |
| US-10195119-B2 | High refractive index addition-fragmentation agents | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2019-02-05 | — | — | US | disclosed |
| US-20160279033-A1 | HIGH REFRACTIVE INDEX ADDITION-FRAGMENTATION AGENTS | 3M INNOVATIVE PROPERTIES COMPANY | 2016-09-29 | — | — | US | disclosed |
| US-20160279033-A1 | HIGH REFRACTIVE INDEX ADDITION-FRAGMENTATION AGENTS | 3M INNOVATIVE PROPERTIES COMPANY | 2016-09-29 | — | — | US | disclosed |
| WO-2014151363-A1 | HIGH REFRACTIVE INDEX ADDITION-FRAGMENTATION AGENTS | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2014-09-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10195119-B2 | High refractive index addition-fragmentation agents | EEF1G, FANCI, EEF1E1 | ADRB2 3626/4885ADRB1 4264/4885ADRB3 3918/4885 |
| US-20160279033-A1 | HIGH REFRACTIVE INDEX ADDITION-FRAGMENTATION AGENTS | EEF1G, FANCI, EEF1E1 | ADRB2 3626/4885ADRB1 4264/4885ADRB3 3918/4885 |
| US-20190105237-A1 | HIGH REFRACTIVE INDEX ADDITION-FRAGMENTATION AGENTS | EEF1G, FANCI, EEF1E1 | ADRB2 3626/4885ADRB1 4264/4885ADRB3 3918/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.