Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | DRD4 | P21917 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | CCKAR | P32238 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | SCN1A | P35498 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.42 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17036157 | 0.90 | LMNA (0.38) | LMNADRD4SLC6A2CCKAROPRM1 | |
| SCHEMBL13872067 | 0.87 | LMNA (0.52) | LMNADRD4SLC6A2CCKAROPRM1 | |
| SCHEMBL16127811 | 0.86 | L3MBTL1 (0.38) | LMNAALDH1A1NPSR1L3MBTL1MAPT | |
| SCHEMBL22213482 | 0.82 | L3MBTL1 (0.35) | LMNAALDH1A1L3MBTL1MAPTMEN1 | |
| SCHEMBL18272058 | 0.82 | CHRM3 (0.38) | LMNAALDH1A1L3MBTL1MAPTMEN1 | |
| SCHEMBL11920351 | 0.81 | MTNR1A (0.36) | TDP1HTTRAB9ANPC1 | |
| SCHEMBL11920353 | 0.81 | AR (0.41) | LMNACYP2D6TDP1MAPTMEN1 | |
| SCHEMBL11920352 | 0.81 | TSHR (0.44) | ALDH1A1TSHR | |
| SCHEMBL13872074 | 0.79 | LMNA (0.46) | LMNADRD4SLC6A2CCKAROPRM1 | |
| SCHEMBL16127934 | 0.79 | SCN1A (0.40) | LMNASCN1ASLC6A3SCN2ASCN3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9730864-B2 | Addition-fragmentation oligomers having high refractive index groups | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2017-08-15 | — | — | US | disclosed |
| US-20160346170-A1 | ADDITION-FRAGMENTATION OLIGOMERS HAVING HIGH REFRACTIVE INDEX GROUPS | 3M INNOVATIVE PROPERTIES COMPANY | 2016-12-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160346170-A1 | ADDITION-FRAGMENTATION OLIGOMERS HAVING HIGH REFRACTIVE INDEX GROUPS | ZYX, MACF1, PYCARD | LMNA 64/4885DRD4 161/4885SLC6A2 4870/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.